Department of Anesthesiology, Aretaieion University Hospital, National and Kapodistrian University of Athens, Greece.
Department of Anesthesiology, Aretaieion University Hospital, National and Kapodistrian University of Athens, Greece.
Int J Surg. 2019 Mar;63:63-70. doi: 10.1016/j.ijsu.2019.02.007. Epub 2019 Feb 12.
This prospective double-blind randomized study aimed at evaluating the short- and long-term postoperative analgesic efficacy of the ultrasound-guided tranversus abdominis plane (TAP) block in inguinal hernia repair under general anesthesia.
Sixty patients undergoing inguinal hernia repair were allocated to TAP block with either ropivacaine 0.75% 20 mL or placebo 20 mL. Postoperatively, they had access to a patient-controlled analgesia (PCA) device administering 1 mg doses of morphine as rescue analgesia. Pain was assessed at rest and during movement with the numeric rating scale (NRS) score 3,6 and 24 hs postoperatively. Other variables recorded were intraoperative dose of remifentanil required to maintain systolic arterial pressure within 20% of baseline, mg of morphine used in the Post Anesthesia Care Unit (PACU) and total dose of morphine administered via the PCA device. Six months after surgery, the occurrence of chronic pain was assessed with the NRS score at rest and during movement. Patients were also asked to fill in the DN4 questionnaire to estimate the development of neuropathic pain.
Patients who were administered ropivacaine demonstrated significantly less pain at rest and on movement, as expressed by NRS scores in comparison to patients in the placebo group. The former group also required less remifentanil intraoperatively, less morphine during the PACU stay and had lower morphine consumption through the PCA device. Six months after surgery, pain scores at rest and during movement were comparable between the two groups. At the same time DN4 scores were low and comparable between the two groups.
Ultrasound-guided TAP block provided better pain control than placebo in the acute setting after inguinal hernia repair. However, the incidence of chronic pain was low and not significantly affected by the performance of the block.
本前瞻性双盲随机研究旨在评估超声引导腹横肌平面(TAP)阻滞在全身麻醉下腹股沟疝修补术中的短期和长期术后镇痛效果。
60 例接受腹股沟疝修补术的患者被分配到 TAP 阻滞组,给予罗哌卡因 0.75%20ml 或安慰剂 20ml。术后,他们可以使用患者自控镇痛(PCA)装置给予 1mg 剂量的吗啡作为解救镇痛。术后 3、6 和 24 小时,通过数字评分量表(NRS)评估静息和运动时的疼痛。记录的其他变量包括术中需要的瑞芬太尼剂量,以维持收缩压在基线的 20%以内、术后恢复室(PACU)使用的吗啡剂量和通过 PCA 装置给予的吗啡总剂量。术后 6 个月,通过 NRS 评分评估静息和运动时的慢性疼痛发生情况。患者还被要求填写 DN4 问卷,以评估神经病理性疼痛的发生。
与安慰剂组相比,接受罗哌卡因治疗的患者在静息和运动时的疼痛明显减轻,NRS 评分较低。前者在术中需要的瑞芬太尼较少,PACU 期间使用的吗啡较少,通过 PCA 装置使用的吗啡也较少。术后 6 个月,两组患者静息和运动时的疼痛评分相似。同时,DN4 评分较低且两组之间无显著差异。
与安慰剂相比,超声引导 TAP 阻滞在腹股沟疝修补术后急性疼痛控制方面效果更好。然而,慢性疼痛的发生率较低,且不受阻滞效果的显著影响。