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诊断性腹腔镜检查阴性的临床疑似阑尾炎患者的再入院和再次手术率:“正常”阑尾不应切除 - 一项回顾性队列研究。

Readmission and reoperation rates following negative diagnostic laparoscopy for clinically suspected appendicitis: The "normal" appendix should not be removed - A retrospective cohort study.

机构信息

Department of Gastrointestinal Surgery, Zealand University Hospital, Denmark.

Gastrounit - Surgical Division, Center for Surgical Research, Copenhagen University Hospital Hvidovre, Denmark.

出版信息

Int J Surg. 2019 Apr;64:1-4. doi: 10.1016/j.ijsu.2019.02.001. Epub 2019 Feb 12.

Abstract

BACKGROUND

In cases with clinically suspected appendicitis, there is controversy regarding the decision to remove a macroscopically normal appearing appendix during laparoscopy when no other intra-abdominal pathology is found. The aim of this study was to examine the rate of appendicitis, along with readmission and reoperation rates following diagnostic laparoscopy of clinically suspected appendicitis in patients where the appendix was not removed.

METHODS

We performed a retrospective cohort analysis of patients who underwent a diagnostic laparoscopy due to clinical suspicion of appendicitis where no other pathology was found and the appendix was not removed. The study period was from 2008 to 2013 and involved patients from two university hospitals in the Copenhagen area.

RESULTS

Of the 271 patients included (81.6% women, median age 27), 56 (20.7%) were readmitted with right iliac fossa pain after a median time of 10 months (range 1-84). Twenty-two patients (8.1%) underwent a new laparoscopic procedure. Appendix was removed in 18 patients, of which only one showed histological signs of inflammation. The median follow-up time was 5.6 years (range 1-109 months).

CONCLUSION

There was a low rate of appendicitis after a previous negative diagnostic laparoscopy. Therefore, based on results from the current study, we do not consider that it is necessary to remove a macroscopic normal appendix during laparoscopy for clinically suspected appendicitis. The high readmission rate warrants the need for further investigation or follow-up.

摘要

背景

在临床上疑似阑尾炎的情况下,对于腹腔镜检查时发现无其他腹腔内病变但阑尾外观正常的情况下是否切除阑尾存在争议。本研究的目的是检查在临床上疑似阑尾炎且未切除阑尾的患者中,行诊断性腹腔镜检查后阑尾炎的发生率、再入院率和再次手术率。

方法

我们对因临床疑似阑尾炎而行诊断性腹腔镜检查且未发现其他病变且未切除阑尾的患者进行了回顾性队列分析。研究期间为 2008 年至 2013 年,涉及哥本哈根地区的两家大学医院的患者。

结果

在纳入的 271 例患者中(81.6%为女性,中位年龄 27 岁),56 例(20.7%)在中位时间 10 个月(1-84 个月)后因右髂窝疼痛再次入院。22 例(8.1%)接受了新的腹腔镜手术。在 18 例切除阑尾的患者中,只有 1 例显示组织学炎症迹象。中位随访时间为 5.6 年(1-109 个月)。

结论

先前阴性诊断性腹腔镜检查后阑尾炎的发生率较低。因此,根据本研究的结果,我们不认为在临床上疑似阑尾炎的情况下有必要在腹腔镜下切除外观正常的阑尾。高再入院率需要进一步调查或随访。

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