Institute of Life Sciences, Jiangsu University, Zhenjiang 212013, Jiangsu, China.
Genes (Basel). 2019 Feb 14;10(2):144. doi: 10.3390/genes10020144.
The vacuolar iron transporter (VIT) proteins are involved in the storage and transport of iron. However, the evolution of this gene family in plants is unknown. In this study, I first identified 114 genes in 14 plant species and classified these genes into seven groups by phylogenetic analysis. Conserved gene organization and motif distribution implied conserved function in each group. I also found that tandem duplication, segmental duplication and transposition contributed to the expansion of this gene family. Additionally, several positive selection sites were identified. Divergent expression patterns of soybean genes were further investigated in different development stages and under iron stress. Functional network analysis exhibited 211 physical or functional interactions. The results will provide the basis for further functional studies of the genes in plants.
液泡铁转运蛋白(VIT)蛋白参与铁的储存和运输。然而,该基因家族在植物中的进化情况尚不清楚。在这项研究中,我首先在 14 种植物物种中鉴定了 114 个基因,并通过系统发育分析将这些基因分为 7 组。保守的基因组织和基序分布表明每个组具有保守的功能。我还发现,串联重复、片段重复和转座子导致了这个基因家族的扩张。此外,还鉴定了几个正选择位点。进一步研究了大豆基因在不同发育阶段和铁胁迫下的差异表达模式。功能网络分析显示了 211 个物理或功能相互作用。这些结果将为植物中基因的进一步功能研究提供基础。