Ben Salah R, Frikha F, Chebbi D, Chabchoub I, Bahloul Z
Service de médecine interne, CHU Hédi Chaker, Sfax, Tunisie.
Service de médecine interne, CHU Hédi Chaker, Sfax, Tunisie.
J Med Vasc. 2019 Feb;44(1):76-78. doi: 10.1016/j.jdmv.2018.11.003. Epub 2018 Dec 12.
Rendu-Osler-Weber syndrome is a rare systemic fibrovascular dysplasia, recognized by mucocutaneous telangiectasias, arteriovenous malformations, epistaxis and family history. Venous thromboembolic disease is a poor prognostic factor in this disease given the risk of increased bleeding caused by anticoagulant therapy. We report a new case of a 56-year-old patient with Osler disease who developed recurrent thromboembolic venous disease when anticoagulants were discontinued. According to a review of the literature, this association does not appear to be fortuitous and is a factor of disease severity.
