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使用乳腺钙和 pH 标准指导催产素催产后的产驹效果和结果。

Efficacy and outcome of foaling augmented with oxytocin using mammary calcium and pH criteria to guide the timing of augmentation.

机构信息

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA.

Department of Clinical Sciences, College of Veterinary Medicine, Cornell University, Ithaca, NY, USA; Department of Veterinary Clinical and Diagnostic Sciences, Faculty of Veterinary Medicine, University of Calgary, Calgary, AB, Canada.

出版信息

Anim Reprod Sci. 2019 Mar;202:87-95. doi: 10.1016/j.anireprosci.2019.02.002. Epub 2019 Feb 8.

Abstract

Augmentation of parturition can be used to advance labor in mares to occur at a time when personnel is available to assist if necessary. We performed a retrospective study to determine the efficacy and safety of augmentation to manage foalings. Augmentation was performed with 3 IU oxytocin i.v. when mammary calcium concentrations were ≥250 ppm, mammary secretion pH ≤ 6.5, and the mare showed impending signs of parturition. Augmented parturitions (n = 19) were compared with three different control groups. The three control groups were: 1) Time Match control (n = 37) which were non-augmented foalings in the barn during the same time period; 2) Mare Match control (n = 32) which were the non-augmented parturitions of the augmented mares in previous years; and 3) Historic Match control (n = 165) consisted of foalings that occurred from 2006 to 2016 in the facility. All augmented mares foaled within two h with an average of 44 min (range 20-75) after oxytocin injection. The interval between foaling and the foal standing was shorter in augmented parturitions compared with historic match controls. The interval between foaling and the foal nursing was longer with augmented parturitions compared with time match and historic match controls. Duration of fetal membrane retention was not different between all groups. Augmentation of imminent parturition is potentially a safe and effective treatment for mares and foals. Implementation of augmentation as a routine procedure may increase the likelihood of enteral administration of colostrum to foals.

摘要

分娩增强可以用于使母马的分娩提前发生,以便在需要时有人手协助。我们进行了一项回顾性研究,以确定增强分娩的功效和安全性,以管理驹的出生。当乳腺钙浓度≥250ppm、乳腺分泌 pH≤6.5 且母马出现即将分娩的迹象时,静脉内给予 3 IU 催产素进行增强分娩。增强分娩(n=19)与三个不同的对照组进行比较。三个对照组分别为:1)时间匹配对照组(n=37),即同期在畜舍中未增强分娩的驹;2)母马匹配对照组(n=32),即前几年增强母马的未增强分娩的驹;3)历史匹配对照组(n=165),由 2006 年至 2016 年在该设施中发生的驹组成。所有增强的母马在催产素注射后 2 小时内分娩,平均为 44 分钟(范围 20-75)。与历史匹配对照组相比,增强分娩的驹出生到站立的间隔更短。与时间匹配和历史匹配对照组相比,增强分娩的驹出生到哺乳的间隔更长。胎膜滞留时间在所有组之间无差异。即将分娩的增强分娩可能是母马和驹的安全有效治疗方法。作为常规程序实施增强分娩可能会增加驹口服初乳的可能性。

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