Soto Álvaro, Morales Gladys, Provoste Rosa, Lanas Fernando, Aliaga Isabel, Pacheco Daniela, Muñoz Sergio
Department of Medical Specialties, Faculty of Medicine, Universidad de La Frontera, Temuco, Chile; Unit of Neurology, Dr. Hernán Henríquez Aravena Hospital, Temuco, Chile; Center for Research in Cardiovascular and Nutritional Epidemiology (EPICYN), Universidad de La Frontera, Temuco, Chile.
Center for Research in Cardiovascular and Nutritional Epidemiology (EPICYN), Universidad de La Frontera, Temuco, Chile; Department of Public Health, Faculty of Medicine, Universidad de La Frontera, Temuco, Chile.
J Stroke Cerebrovasc Dis. 2019 May;28(5):1311-1316. doi: 10.1016/j.jstrokecerebrovasdis.2019.01.029. Epub 2019 Feb 14.
There is evidence of a greater incidence of stroke in native populations and minorities. A total of 34% of the population in the Araucanía Region is indigenous. The association between Mapuche ethnicity and stroke is unknown. The aim of the study was to estimate the magnitude of the association between Mapuche ethnicity and stroke occurrence in patients admitted to the Dr. Hernán Henríquez Aravena Hospital (HHHA) in Temuco, Chile.
We performed an incident case-control-paired study with patients hospitalized with an acute stroke in the internal medicine service and controls from other medical services at the HHHA. One control was selected for each case, matched by gender and age (±5 years).
A total of 104 nonconsecutive cases of stroke were included. The proportion of Mapuche individuals was similar between cases and controls (27.9% and 32.7%, respectively, P = .45). Hypertension and overweight-obesity were associated with stroke. Low socioeconomic status, rurality, diabetes, and smoking were associated with Mapuche ethnicity. In the conditional logistic regression model, Mapuche ethnicity was not associated with stroke. The odds ratio was .75 (P = .47, 95% confidence intervals: .35-1.62).
There is no statistically significant evidence in the study to support the hypothesis of an association between Mapuche ethnicity and stroke. None of the control variables modified the effect of ethnicity on stroke.
有证据表明，原住民和少数族裔中风发病率更高。阿劳卡尼亚地区34%的人口为原住民。马普切族与中风之间的关联尚不清楚。本研究的目的是评估智利特木科市埃尔南·恩里克斯·阿拉韦纳博士医院（HHHA）收治的患者中，马普切族与中风发生之间的关联程度。
我们对内科服务中因急性中风住院的患者以及HHHA其他医疗服务中的对照者进行了一项病例对照配对研究。为每个病例选择一名对照者，按性别和年龄（±5岁）进行匹配。
共纳入104例非连续性中风病例。病例组和对照组中马普切族个体的比例相似（分别为27.9%和32.7%，P = 0.45）。高血压和超重肥胖与中风相关。社会经济地位低、农村地区、糖尿病和吸烟与马普切族相关。在条件逻辑回归模型中，马普切族与中风无关。比值比为0.75（P = 0.47，95%置信区间：0.35 - 1.62）。
本研究中没有统计学上的显著证据支持马普切族与中风之间存在关联的假设。没有一个控制变量改变族裔对中风的影响。
