Deveney Christen M
Department of Psychology, Wellesley College, 106 Central Street, Wellesley, MA, 02481, USA.
Biol Psychol. 2019 Apr;143:1-9. doi: 10.1016/j.biopsycho.2019.02.002. Epub 2019 Feb 14.
Despite increasing interest in the mechanisms of irritability, little research in this domain has been conducted with adults. The present study evaluates relationships among trait irritability, reward responsivity, and frustrative non-reward in a non-clinical sample of young adult females (n = 58) using a paradigm that has been used successfully in pediatric populations with clinically significant irritability. Similar to prior work in these pediatric populations, the frustration manipulation increased self-reported frustration and decreased task accuracy on trials requiring spatial attention shifts. Higher trait irritability was associated with smaller FRN amplitudes to loss feedback. Trait irritability was unrelated to the FRN to reward feedback and the reward positivity ERP. These findings provide preliminary evidence linking irritability with aberrant frustrative non-reward in a healthy young adult sample.
尽管人们对易怒机制的兴趣与日俱增，但该领域针对成年人的研究却很少。本研究采用一种已在有临床显著易怒症状的儿科人群中成功应用的范式，对58名年轻成年女性的非临床样本中的特质易怒性、奖励反应性和挫折性无奖励之间的关系进行了评估。与这些儿科人群之前的研究工作类似，挫折操纵增加了自我报告的挫折感，并降低了需要空间注意力转移的试验中的任务准确性。较高的特质易怒性与对损失反馈的较小FRN波幅相关。特质易怒性与奖励反馈的FRN以及奖励正性ERP无关。这些发现为在健康的年轻成人样本中将易怒性与异常的挫折性无奖励联系起来提供了初步证据。
