Regis University School of Pharmacy, Denver, Colo.
University of Colorado, Denver, Colo; American University of Armenia, Yerevan, Armenia.
J Allergy Clin Immunol Pract. 2019 Jul-Aug;7(6):1835-1842.e2. doi: 10.1016/j.jaip.2019.01.055. Epub 2019 Feb 15.
Examining national trends in asthma treatment and control is essential to inform treatment and public health initiatives.
Explore national trends in asthma control and treatment over time among children and those residing in poor-urban areas.
This was an analysis of trends from 2003 to 2014 among children (aged 1-17 years) in the Medical Expenditure Panel Survey. Indicators of poor control included use of more than 3 canisters of short-acting β-agonists (SABAs) in 3 months, asthma attack, emergency department/inpatient hospitalization, and systemic corticosteroids. Treatment included inhaled corticosteroids, controller medications, SABAs, and greater than or equal to 0.7 ratio of controller-to-total prescriptions. Other measures included the number of asthma medications, outpatient visits, asthma-specific drug, and total expenditures per-patient-per-year.
There were 8.4 million children with asthma in the United States in 2014; 11.1% lived in poor-urban areas. There was a statistically significant decrease in the percentage of children using inhaled corticosteroids, controller medications, daily preventive medications, systemic corticosteroids, SABAs, more than 3 canisters of SABAs (in 3 months), overall asthma prescriptions, and outpatient visits. There was a significant increase in the percentage of children reporting having an asthma attack. Trends for children residing in poor-urban areas were compared with all others; however, limited data and variability in annual estimates prevent clear conclusions.
Results suggest lack of improvement in treatment and control since 2003 among children with asthma in the United States. There is significant room for improvement in asthma control and disease management among children.
检查哮喘治疗和控制的国家趋势对于指导治疗和公共卫生措施至关重要。
探讨儿童和贫困城市地区哮喘控制和治疗的国家趋势随时间的变化。
这是对 2003 年至 2014 年期间儿童(1-17 岁)医疗支出调查中的趋势进行的分析。控制不佳的指标包括在 3 个月内使用超过 3 罐短效 β-激动剂(SABA)、哮喘发作、急诊室/住院治疗和全身皮质类固醇。治疗包括吸入皮质类固醇、控制药物、SABA 以及控制器药物与总处方的比值大于或等于 0.7。其他措施包括哮喘药物的数量、门诊就诊次数、哮喘专用药物和每位患者每年的总支出。
2014 年美国有 840 万儿童患有哮喘,其中 11.1%生活在贫困城市地区。使用吸入皮质类固醇、控制药物、每日预防药物、全身皮质类固醇、SABA、3 个月内超过 3 罐 SABA(在 3 个月内)、总体哮喘处方和门诊就诊的儿童比例均呈统计学显著下降。报告哮喘发作的儿童比例显著增加。将生活在贫困城市地区的儿童与其他所有儿童的趋势进行了比较;然而,数据有限且年度估计值的变异性使得无法得出明确的结论。
结果表明,自 2003 年以来,美国哮喘儿童的治疗和控制情况并未改善。儿童哮喘控制和疾病管理仍有很大的改善空间。