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基于倾向评分匹配的慢性阻塞性肺疾病患者社会/情感支持与生活质量、抑郁和残疾的关系分析。

Relationships Between Social/Emotional Support and Quality of Life, Depression and Disability in Patients With Chronic Obstructive Pulmonary Disease: An Analysis Based on Propensity Score Matching.

机构信息

Department of Pharmacy Practice and Administrative Sciences, College of Pharmacy, University of New Mexico, Albuquerque, NM, USA.

Department of Pharmacy Practice, Faculty of Pharmacy, Yarmouk University, Irbid, Jordan.

出版信息

Ann Behav Med. 2019 Aug 29;53(10):918-927. doi: 10.1093/abm/kaz002.

DOI:10.1093/abm/kaz002
PMID:30773583
Abstract

BACKGROUND

Patients with chronic obstructive pulmonary diseases (COPD) suffer from impaired Health-Related Quality of Life (HRQoL). Having an adequate social/emotional support may improve the quality of life of COPD patients.

OBJECTIVE

To study the relationships between social/emotional support and HRQoL, depression and disability among patients with COPD.

METHODS

We applied a propensity score model using data from a large U.S. population-based health survey to match COPD patients who reported rarely/never receiving social/emotional support with those who received that support. Social/emotional support and all dependent variables were dichotomized into yes/no responses. For HRQoL domains, number of days of poor physical or mental health and activity limitations, "yes" indicated ≥14 unhealthy days in the last 30 days. McNemar's test was used to compare the matched groups.

RESULTS

Social/emotional support was rarely/never received by 37% of responders. Standardized differences between matched groups, after propensity score matching, were less than 10% indicating successful matching. COPD patients who rarely/never receive social/emotional support were more likely to report: depression (n = 321 pairs, odds ratio (OR) = 2.2, 95% confidence interval (CI): 1.56-3.14, p < .001), ≥14 poor mental HRQoL days (n = 310 pairs, OR = 3.12, 95% CI: 2.1-4.73, p < .001) and ≥14 poor physical HRQoL days (n = 307 pairs, OR = 1.5, 95% CI: 1.06-2.13, p = .02). There were no significant differences in general health, disability, or activity limitations.

CONCLUSION

Among COPD patients, lower levels of social/emotional support are associated with depression and deterioration of mental and physical HRQoL. The importance of social/emotional support should be emphasized by policy makers, healthcare providers, and family members, to improve functioning among COPD patients.

摘要

背景

慢性阻塞性肺疾病(COPD)患者的健康相关生活质量(HRQoL)受损。获得足够的社会/情感支持可能会改善 COPD 患者的生活质量。

目的

研究社会/情感支持与 COPD 患者的 HRQoL、抑郁和残疾之间的关系。

方法

我们应用倾向评分模型,使用来自美国大型基于人群的健康调查的数据,将报告很少/从未获得社会/情感支持的 COPD 患者与获得该支持的患者进行匹配。社会/情感支持和所有因变量均分为是/否回答。对于 HRQoL 领域,身体或心理健康不佳以及活动受限的天数,“是”表示在过去 30 天内有≥14 天的不健康日子。采用 McNemar 检验比较匹配组。

结果

37%的应答者很少/从未获得社会/情感支持。倾向评分匹配后,匹配组之间的标准化差异小于 10%,表明匹配成功。很少/从未获得社会/情感支持的 COPD 患者更有可能报告:抑郁(n=321 对,优势比(OR)=2.2,95%置信区间(CI):1.56-3.14,p<0.001)、≥14 天的心理健康 HRQoL 较差(n=310 对,OR=3.12,95%CI:2.1-4.73,p<0.001)和≥14 天的身体健康 HRQoL 较差(n=307 对,OR=1.5,95%CI:1.06-2.13,p=0.02)。在一般健康、残疾或活动受限方面没有显著差异。

结论

在 COPD 患者中,较低水平的社会/情感支持与抑郁和心理健康及身体 HRQoL 的恶化有关。政策制定者、医疗保健提供者和家庭成员应强调社会/情感支持的重要性,以改善 COPD 患者的功能。

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