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综合和去卷积组学方法揭示根瘤农杆菌在植物肿瘤中的生活方式。

Integrative and deconvolution omics approaches to uncover the Agrobacterium tumefaciens lifestyle in plant tumors.

机构信息

a Institute for integrative biology of the cell (I2BC), CNRS CEA Univ. Paris-Sud , University Paris-Saclay , Gif-sur-Yvette , France.

出版信息

Plant Signal Behav. 2019;14(3):e1581562. doi: 10.1080/15592324.2019.1581562. Epub 2019 Feb 17.

Abstract

Agrobacterium tumefaciens is a plant pathogen which provokes galls on roots and stems (crown-gall disease) and colonizes them. Two approaches combining omics were used to decipher the lifestyle of A. tumefaciens in plant tumors: an integrative approach when omics were used on A. tumefaciens cells collected from plant tumors, a deconvolution approach when omics were used on A. tumefaciens cells exploiting a single tumor metabolite in pure culture assay. This addendum highlights some recent results on the biotroph lifestyle of A. tumefaciens in plant tumors.

摘要

根癌农杆菌是一种植物病原体,可在根和茎上引起肿瘤(冠瘿病)并定植在上面。两种结合了组学的方法被用于破译根癌农杆菌在植物肿瘤中的生活方式:一种是整合方法,当组学用于从植物肿瘤中收集的根癌农杆菌细胞时;另一种是去卷积方法,当组学用于在纯培养试验中利用单个肿瘤代谢物的根癌农杆菌细胞时。本文增刊重点介绍了根癌农杆菌在植物肿瘤中的生物营养生活方式的一些最新研究成果。

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