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高危患者膝上截肢的周围神经阻滞

Peripheral nerve blocks for above knee amputation in high-risk patients.

作者信息

Chandran Rajkumar, Beh Zhi Yuen, Tsai Fung Chen, Kuruppu Suran Dhanushka, Lim Jia Yin

机构信息

Department of Anesthesia and Intensive Care, Changi General Hospital, Singapore.

出版信息

J Anaesthesiol Clin Pharmacol. 2018 Oct-Dec;34(4):458-464. doi: 10.4103/joacp.JOACP_346_17.

Abstract

BACKGROUND AND AIMS

Above knee amputation (AKA) is associated with considerable mortality and morbidity. There is paucity of data describing the use of peripheral nerve blocks (PNB) as the sole anesthetic technique in high-risk patients undergoing AKA. Our objectives were to evaluate the use of PNB as sole anesthetic technique in the above-mentioned population and its clinical outcomes.

MATERIAL AND METHODS

This was a retrospective descriptive study conducted in a tertiary hospital. For this study, patients with American Society of Anesthesiologist [ASA] IV physical status underwent AKA using PNB between January 2010 and December 2016, were identified. The primary outcome measured was the success of the operation. The secondary outcomes were block details, intraoperative hemodynamics, usage of sedation and analgesia, patients' comorbidities, mortality rates at 30 days and one year.

RESULTS

Out of fifty-seven patients, the median age (interquartile range) was 74 (57 - 81) years and 60% were males. The results show 91% successfully underwent surgery with PNB (95% CI 81% to 96%). 95% required intraoperative sedation and analgesia. 67% received combined femoral, obturator and sciatic nerve blocks, in which nine cases had an additional lateral femoral cutaneous nerve block. Interestingly, 33% only received combined femoral and sciatic nerve blocks, and they required higher sedation analgesia (p = 0.013). The 30-day and one-year mortality were 12.3% & 47.4%. Majority had stable hemodynamics during the surgery.

CONCLUSION

This study shows that PNB is a viable option for reliable anesthesia for AKA in high-risk patients. Combined FOS nerve block would reduce the dose for sedation-analgesia during the operation.

摘要

背景与目的

膝上截肢(AKA)与相当高的死亡率和发病率相关。关于将外周神经阻滞(PNB)作为接受AKA的高危患者唯一麻醉技术的使用情况,数据匮乏。我们的目标是评估PNB作为上述人群唯一麻醉技术的使用情况及其临床结果。

材料与方法

这是一项在三级医院进行的回顾性描述性研究。在本研究中,确定了2010年1月至2016年12月期间使用PNB接受AKA的美国麻醉医师协会(ASA)IV级身体状况的患者。测量的主要结局是手术的成功与否。次要结局包括阻滞细节、术中血流动力学、镇静和镇痛的使用情况、患者的合并症、30天和1年的死亡率。

结果

在57例患者中,中位年龄(四分位间距)为74(57-81)岁,60%为男性。结果显示,91%的患者通过PNB成功接受了手术(95%置信区间81%至96%)。95%的患者术中需要镇静和镇痛。67%的患者接受了股神经、闭孔神经和坐骨神经联合阻滞,其中9例还额外进行了股外侧皮神经阻滞。有趣的是,33%的患者仅接受了股神经和坐骨神经联合阻滞,且他们需要更高剂量的镇静镇痛(p=0.013)。30天和1年的死亡率分别为12.3%和47.4%。大多数患者在手术期间血流动力学稳定。

结论

本研究表明,PNB是高危患者AKA可靠麻醉的可行选择。联合FOS神经阻滞可减少术中镇静镇痛的剂量。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/0fc7/6360901/3194646a82f4/JOACP-34-458-g001.jpg

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