Farhang Borzoo, Lesiak Alex C, Ianno Daniel J, Minasyan Hayk, Shafritz Adam B, Viscomi Christopher M
Department of Anesthesiology, University of Vermont Medical Center, Burlington, VT, USA.
Department of Orthopedic Surgery, University of Vermont College of Medicine, Burlington, VT, USA.
J Anaesthesiol Clin Pharmacol. 2018 Oct-Dec;34(4):507-512. doi: 10.4103/joacp.JOACP_69_16.
Intravenous regional anesthesia (IVRA) is utilized for upper extremity surgery, but higher tourniquet pressure and longer inflation time increase the risk of soft tissue and nerve injury. We investigated the duration and magnitude of elevated venous pressure during IVRA to assess the possibility of safely lowering the tourniquet pressure during surgery.
Twenty adult patients scheduled for distal upper extremity surgery were enrolled. An additional intravenous catheter was placed in the surgical arm connected to a digital pressure transducer for monitoring venous pressure. Venous pressure was recorded prior to IVRA and every 30 s after injection of local anesthetic (LA) until the completion of surgery.
All 20 subjects completed the study without complication. Peak venous pressure was 340 mmHg in one patient which lasted for less than 30 s. Mean venous pressures fell below systolic blood pressure after 4.5 min in all cases except one. This patient had elevated venous pressures for 24 of 25 min of tourniquet time exceeding systolic blood pressure. The only statistically significant intraoperative factor associated with elevated venous pressure was elevated peak systolic pressure ( = 0.001).
We found that the mean peak venous pressure was below systolic blood pressure in only 14 of the 20 subjects, and the peak injection pressure exceeded 300 mmHg in one patient. Another patient's venous pressure remained above systolic blood pressure for 24 of 25 min of tourniquet time. Current precautions to prevent LA toxicity may be insufficient in some patients and attempts to lower tourniquet pressures to just above systolic blood pressures soon after IVRA injection may result in toxicity, specifically if systolic pressure is elevated.
静脉区域麻醉(IVRA)用于上肢手术,但较高的止血带压力和较长的充气时间会增加软组织和神经损伤的风险。我们研究了IVRA期间静脉压力升高的持续时间和幅度,以评估在手术期间安全降低止血带压力的可能性。
纳入20例计划行上肢远端手术的成年患者。在手术手臂上额外放置一根静脉导管,连接数字压力传感器以监测静脉压力。在IVRA前及注射局部麻醉药(LA)后每30秒记录静脉压力,直至手术结束。
所有20名受试者均无并发症完成研究。1例患者的静脉压峰值为340 mmHg,持续时间少于30秒。除1例患者外,所有病例在4.5分钟后平均静脉压均降至收缩压以下。该患者在止血带充气25分钟中的24分钟内静脉压升高,超过收缩压。与静脉压升高相关的唯一具有统计学意义的术中因素是收缩压峰值升高(P = 0.001)。
我们发现,20名受试者中只有14人的平均静脉压峰值低于收缩压,1例患者的注射压力峰值超过300 mmHg。另1例患者在止血带充气25分钟中的24分钟内静脉压一直高于收缩压。目前预防LA毒性的措施在某些患者中可能不足,在IVRA注射后不久试图将止血带压力降至略高于收缩压可能会导致毒性,特别是在收缩压升高的情况下。