DNA polymerases as chemotherapy targets: promise and challenges.
作者信息
Eckert Kristin A, Barnes Ryan P
机构信息
Department of Pathology, Pennsylvania State University, The Jake Gittlen Laboratories for Cancer Research, Hershey, PA, USA.
出版信息
Oncotarget. 2019 Jan 18;10(6):620-621. doi: 10.18632/oncotarget.26572.
Abstract
摘要
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Cancer Res. 2018 Dec 1;78(23):6549-6560. doi: 10.1158/0008-5472.CAN-17-3931. Epub 2018 Oct 8.
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Targeting ATR in cancer.在癌症中靶向 ATR。
Nat Rev Cancer. 2018 Sep;18(9):586-595. doi: 10.1038/s41568-018-0034-3.
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A Small-Molecule Inhibitor of Human DNA Polymerase η Potentiates the Effects of Cisplatin in Tumor Cells.一种人DNA聚合酶η的小分子抑制剂增强顺铂在肿瘤细胞中的作用。
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