Iyer Sravisht, Kim Han Jo, Theologis Alexander, Nemani Venu M, Albert Todd J, Lenke Lawrence G, Burch Shane, Boachie-Adjei Oheneba, Deviren Vedat, Protopsaltis Themistocles S, Smith Justin S, Scheer Justin K, Mizutani Jun, Kleinberg Eric O, Ames Christopher P
Hospital for Special Surgery, New York, NY, USA.
Weill Cornell Medical College, New York, NY, USA.
Global Spine J. 2019 Feb;9(1):6-13. doi: 10.1177/2192568217705655. Epub 2018 May 10.
Retrospective cohort study.
Determine the indications, complications, and clinical outcomes in patients requiring fusions from the cervical spine to the pelvis. Several investigators have examined fusions from the thoracic spine to the sacrum, but no similar study has been performed for cervical-to-pelvis fusions.
Patients from 2003 to 2014 with an upper instrumented vertebrae (UIV) in the cervical spine (any level) and a lower instrumented vertebrae (LIV) in the sacrum or pelvis were included in the study. Those with infectious or acute trauma-related deformities were excluded. Patient demographics, medical history, diagnosis, operative procedure, and health-related quality of life measures were analyzed. Student's test, Kruskal-Wallis test, and χ test were used as appropriate; significance was set at < .05 for all tests.
Fifty-five patients met inclusion criteria for the study. Average follow-up was 2.8 years. Proximal junctional kyphosis was the most common indication for cervical-to-pelvis fusions (36%). The most common UIV was C2 (29%) followed by C7 (24%). There was an average 31° correction in maximum kyphosis and a 3.3cm improvement in sagittal vertical axis. In adults, the rate of complication was 71.4%, with a major complication rate of 39.3% and reoperation rate of 53.6%. There was significant improvement in the Scoliosis Research Society (SRS-22r) score (3.0 to 3.5; < .01).
Proximal junctional kyphosis is the most common indication for patients requiring fusion to the cervical spine. Adult patients incur a significant risk of major complications and reoperations. However, significant improvement in SRS-22r outcomes are noted in these patients.
回顾性队列研究。
确定需要从颈椎至骨盆进行融合手术的患者的手术指征、并发症及临床结局。已有多位研究者对胸椎至骶骨的融合手术进行了研究,但尚未有针对颈椎至骨盆融合手术的类似研究。
纳入2003年至2014年间,颈椎(任何节段)有上位固定椎体(UIV)且骶骨或骨盆有下位固定椎体(LIV)的患者。排除患有感染性或急性创伤相关畸形的患者。分析患者的人口统计学资料、病史、诊断、手术过程及健康相关生活质量指标。根据情况使用学生t检验、Kruskal-Wallis检验和χ检验;所有检验的显著性设定为P <.05。
55例患者符合该研究的纳入标准。平均随访时间为2.8年。近端交界性后凸是颈椎至骨盆融合手术最常见的指征(36%)。最常见的UIV为C2(29%),其次是C7(24%)。最大后凸平均矫正31°,矢状垂直轴改善3.3厘米。在成人中,并发症发生率为71.4%,主要并发症发生率为39.3%,再次手术率为53.6%。脊柱侧弯研究学会(SRS-22r)评分有显著改善(从3.0提高到3.5;P <.01)。
近端交界性后凸是需要进行颈椎融合手术患者最常见的指征。成年患者发生重大并发症和再次手术的风险较高。然而,这些患者的SRS-22r结局有显著改善。