Siwapituk Wisaneeya, Kitisomprayoonkul Wasuwat
Department of Physiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Department of Rehabilitation Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Osteoporos Sarcopenia. 2016 Mar;2(1):41-44. doi: 10.1016/j.afos.2016.02.005. Epub 2016 Mar 21.
Treadmill walking is a cheap and attainable form of exercise, which carries a low injury risk and confers other health benefit. The aim of this study is to investigate the effects of 3-month treadmill walking on biochemical bone markers in Thai postmenopausal women.
Thai postmenopausal women participated in a 3-month supervised treadmill walking program. The program consisted of treadmill walking, the intensity of which was 55-70% of maximal heart rate, with duration of 30 min per day, at a frequency of 3 days a week. Crosslinked C-terminal telopeptides of type I collagen (CTX-I) and N-terminal propeptides of type I procollagen (PINP) level were measured at baseline and at 1 week after 3-month training.
Eighteen women completed the training program. The average age of patients was 59.39 ± 4.18 years. The average period after menopause was 9.28 ± 6.52 years. CTX-I and PINP levels at baseline were 0.43 ± 0.14 and 52.15 ± 13.43 ng/ml. CTX-I and PINP levels after 3-month training were 0.80 ± 0.26 and 66.77 ± 22.82 ng/ml. Bone resorption and formation markers were significantly increased after treadmill walking (p < 0.01).
Bone turnover increases after 3-month supervised treadmill walking in Thai postmenopausal women.
跑步机行走是一种成本低廉且易于实现的运动形式，受伤风险低且具有其他健康益处。本研究旨在调查为期3个月的跑步机行走对泰国绝经后女性生化骨标志物的影响。
泰国绝经后女性参加了一项为期3个月的有监督的跑步机行走计划。该计划包括跑步机行走，强度为最大心率的55-70%，每天持续30分钟，每周3次。在基线时以及3个月训练后的第1周测量I型胶原交联C末端肽（CTX-I）和I型前胶原N末端前肽（PINP）水平。
18名女性完成了训练计划。患者的平均年龄为59.39±4.18岁。绝经后的平均时间为9.28±6.52年。基线时CTX-I和PINP水平分别为0.43±0.14和52.15±13.43 ng/ml。3个月训练后CTX-I和PINP水平分别为0.80±0.26和66.77±22.82 ng/ml。跑步机行走后骨吸收和形成标志物显著增加（p<0.01）。
在泰国绝经后女性中，经过3个月有监督的跑步机行走后骨转换增加。
