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在泰国绝经后女性中,在监督下进行跑步机行走期间骨转换增加。

Bone turnover increases during supervised treadmill walking in Thai postmenopausal women.

作者信息

Siwapituk Wisaneeya, Kitisomprayoonkul Wasuwat

机构信息

Department of Physiology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Department of Rehabilitation Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

Osteoporos Sarcopenia. 2016 Mar;2(1):41-44. doi: 10.1016/j.afos.2016.02.005. Epub 2016 Mar 21.

Abstract

INTRODUCTION

Treadmill walking is a cheap and attainable form of exercise, which carries a low injury risk and confers other health benefit. The aim of this study is to investigate the effects of 3-month treadmill walking on biochemical bone markers in Thai postmenopausal women.

MATERIAL AND METHODS

Thai postmenopausal women participated in a 3-month supervised treadmill walking program. The program consisted of treadmill walking, the intensity of which was 55-70% of maximal heart rate, with duration of 30 min per day, at a frequency of 3 days a week. Crosslinked C-terminal telopeptides of type I collagen (CTX-I) and N-terminal propeptides of type I procollagen (PINP) level were measured at baseline and at 1 week after 3-month training.

RESULTS

Eighteen women completed the training program. The average age of patients was 59.39 ± 4.18 years. The average period after menopause was 9.28 ± 6.52 years. CTX-I and PINP levels at baseline were 0.43 ± 0.14 and 52.15 ± 13.43 ng/ml. CTX-I and PINP levels after 3-month training were 0.80 ± 0.26 and 66.77 ± 22.82 ng/ml. Bone resorption and formation markers were significantly increased after treadmill walking (p < 0.01).

CONCLUSION

Bone turnover increases after 3-month supervised treadmill walking in Thai postmenopausal women.

摘要

引言

跑步机行走是一种成本低廉且易于实现的运动形式,受伤风险低且具有其他健康益处。本研究旨在调查为期3个月的跑步机行走对泰国绝经后女性生化骨标志物的影响。

材料与方法

泰国绝经后女性参加了一项为期3个月的有监督的跑步机行走计划。该计划包括跑步机行走,强度为最大心率的55-70%,每天持续30分钟,每周3次。在基线时以及3个月训练后的第1周测量I型胶原交联C末端肽(CTX-I)和I型前胶原N末端前肽(PINP)水平。

结果

18名女性完成了训练计划。患者的平均年龄为59.39±4.18岁。绝经后的平均时间为9.28±6.52年。基线时CTX-I和PINP水平分别为0.43±0.14和52.15±13.43 ng/ml。3个月训练后CTX-I和PINP水平分别为0.80±0.26和66.77±22.82 ng/ml。跑步机行走后骨吸收和形成标志物显著增加(p<0.01)。

结论

在泰国绝经后女性中,经过3个月有监督的跑步机行走后骨转换增加。

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Bone turnover markers after the menopause: T-score approach.绝经后骨转换标志物:T 评分法。
Bone. 2018 Jun;111:44-48. doi: 10.1016/j.bone.2018.03.016. Epub 2018 Mar 15.

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