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诊断性心导管检查在先天性心脏病患儿中的作用:本地经验

The role of diagnostic cardiac catheterization for children with congenital heart diseases: local experience.

作者信息

Wagdy Reham

机构信息

Department of Pediatrics, Faculty of Medicine, Alexandria University, Alexandria, Egypt.

出版信息

Arch Med Sci Atheroscler Dis. 2018 Jun 28;3:e72-e79. doi: 10.5114/amsad.2018.76824. eCollection 2018.

Abstract

INTRODUCTION

Despite the development of non-invasive tools of investigations for congenital heart diseases (CHDs), still the role of diagnostic cardiac catheterization (DCC) cannot be undermined. The study aimed to analyze the clinical profile of indicated CHDs cases at our center for DCC to evaluate the contribution of DCC in patients' management plans.

MATERIAL AND METHODS

The study checked files of cases performed DCC between 2011 and 2012 at the pediatric catheterization unit of Alexandria University Children's Hospital by the same operator. Demographic, laboratory and hemodynamic data were collected and analyzed.

RESULTS

Files of 61 children were included in the study. They were grouped into: group I (GI) ( = 25) with pulmonary hypertension (PH), and group II (GII) ( = 36) cases with obstructive pulmonary artery diseases. For the PH group, ventricular septal defect (VSD) was the most common (55%), and patients' outcome plans were based on angiography - operable subgroup GI-A: (84%) ( = 21) and non-operable (16%) GI-B: (4% inoperable, 12% recommended for sildenafil). GI-B cases were significantly older, with higher PVRI and PVRI/SVRI (3.62, 0.68, = 0.002) compared to GI-A (0.89, 0.23, = 0.002, respectively). For group II, tetralogy of Fallot (TOF) was predominant (60%) among the disease spectrum, and the McGoon ratio ranged from 0.7 to 3.2 (median: 1.8). Outcome for GII: 63% operable, 25% shunt, 12% stent. Only pulmonary atresia cases showed a significant difference in the unmatched plans between echocardiography and catheterization reports (χ = 7.438, = 0.023).

CONCLUSIONS

Diagnostic cardiac catheterization had a positive contribution for determination of the management plans for more than 84% of cases. The utility of pediatric cardiac catheterization in diagnosis should be adjusted according to the local needs of every cardiac center.

摘要

引言

尽管先天性心脏病(CHD)的无创检查工具不断发展,但诊断性心导管检查(DCC)的作用仍不可忽视。本研究旨在分析我院接受DCC的CHD患者的临床特征,以评估DCC在患者管理计划中的作用。

材料与方法

本研究查阅了2011年至2012年在亚历山大大学儿童医院儿科导管室由同一操作者进行DCC的病例档案。收集并分析了人口统计学、实验室和血流动力学数据。

结果

61例儿童病例纳入研究。他们被分为:第一组(GI)(n = 25)患有肺动脉高压(PH),第二组(GII)(n = 36)患有阻塞性肺动脉疾病。对于PH组,室间隔缺损(VSD)最为常见(55%),患者的治疗方案基于血管造影——可手术亚组GI-A:(84%)(n = 21)和不可手术组GI-B:(16%)(4%不可手术,12%推荐使用西地那非)。与GI-A组(分别为0.89、0.23,P = 0.002)相比,GI-B组病例年龄显著更大,肺血管阻力指数(PVRI)和PVRI/体循环血管阻力指数(SVRI)更高(分别为3.62、0.68,P = 0.002)。对于第二组,法洛四联症(TOF)在疾病谱中占主导(60%),McGoon比值范围为0.7至3.2(中位数:1.8)。GII组的治疗结果:63%可手术,25%分流,12%置入支架。仅肺动脉闭锁病例在超声心动图和导管检查报告的不匹配方案中存在显著差异(χ² = 7.438,P = 0.023)。

结论

诊断性心导管检查对超过84%的病例治疗方案的确定有积极作用。儿科心导管检查在诊断中的实用性应根据每个心脏中心的当地需求进行调整。

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