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印度东部一家三级医疗中心0至12岁年龄组先天性心脏病的临床和超声心动图特征:一项回顾性横断面研究

Clinical and Echocardiographic Profile of Congenital Heart Diseases in the 0-12-Year Age Group in a Tertiary Care Medical Institute in Eastern India: A Retrospective, Cross-Sectional Study.

作者信息

Kishore Sunil, Kumar Manish, Kumar Amit, Gupta Anand, Chandan Chandrabhanu, Anshuman Anshuman, Prakash Jayant, Sinha Shalini, Kumar Neeraj

机构信息

Pediatrics, Indira Gandhi Institute of Medical Sciences, Patna, IND.

Cardiology, Indira Gandhi Institute of Medical Sciences, Patna, IND.

出版信息

Cureus. 2022 Jun 20;14(6):e26114. doi: 10.7759/cureus.26114. eCollection 2022 Jun.

Abstract

Background This study aimed to determine the clinical and echocardiography profile of congenital heart diseases (CHDs) among admitted children as well as patients presenting to the outpatient department of the Indira Gandhi Institute of Medical Sciences, Patna, which is a tertiary care and apex institute located in Bihar, India. Methodology A retrospective, cross-sectional study was conducted in a tertiary care hospital from January 2019 to January 2021. In total, 200 patients aged 0-12 were enrolled in the study. The study design was exploratory, with a proforma drafted to study patients with features suggestive of CHDs. All pediatric echocardiography was performed by a trained cardiologist. Records were obtained from the departmental record-keeping register, and reports were available for analyzing the data. For data collection, cardiology and pediatric department registers were reviewed and all CHD data were collected. Data analysis was done using SPSS software version 25.0 (IBM Corp., Armonk, NY, USA). Results Of the 200 children with CHDs, 142 were diagnosed to have acyanotic heart disease (ACHD), while 58 had cyanotic congenital heart disease (CCHD). Among 200 cases of CHD, ventricular septal defect (VSD) constituted 62 cases comprising 31% of the total CHD cases and 44% of all ACHD cases. Atrial septal defect (ASD) was the second most common CHD comprising 23% of all CHD cases. Tetralogy of Fallot (TOF) constituted 23 cases accounting for 11.5% of all CHD cases. It was the most common CCHD. Based on the age at the time of presentation, 90 (45%) cases were diagnosed below one year of age. Congestive heart failure (CHF) was most common in ACHD comprising 30% compared to CCHD in which only 7% of cases had CHF. This finding was statistically significant (p < 0.05). Analyzing the symptoms of different CHDs, of both ACHDs and CCHDs, the common symptoms were fast breathing (38%). Conclusions Among ACHD patients, 31% VSD and 21% ASD were noted. In CCHD, TOF was the most common with 11.5% of cases. Respiratory tract conditions were the most common comorbidities encountered. Because this is one of the first studies conducted in Bihar in the pediatric age group, it can help know the prevalence of CHDs in this region and will be useful for developing policies by stakeholders.

摘要

背景 本研究旨在确定印度比哈尔邦一家三级医疗和顶级医疗机构——巴特那英迪拉·甘地医学科学研究所收治儿童以及门诊患者中先天性心脏病(CHD)的临床和超声心动图特征。

方法 2019年1月至2021年1月在一家三级医疗医院进行了一项回顾性横断面研究。总共200名年龄在0至12岁的患者纳入研究。研究设计为探索性,制定了一份表格以研究具有CHD特征的患者。所有儿科超声心动图检查均由一名经过培训的心脏病专家进行。记录从科室记录登记簿中获取,报告可供分析数据。为收集数据,查阅了心脏病学和儿科科室登记簿并收集了所有CHD数据。使用SPSS软件25.0版(美国纽约州阿蒙克市IBM公司)进行数据分析。

结果 在200例CHD患儿中,142例被诊断为非青紫型心脏病(ACHD),58例患有青紫型先天性心脏病(CCHD)。在200例CHD病例中,室间隔缺损(VSD)有62例,占CHD病例总数的31%,占所有ACHD病例的44%。房间隔缺损(ASD)是第二常见的CHD,占所有CHD病例的23%。法洛四联症(TOF)有23例,占所有CHD病例的11.5%。它是最常见的CCHD。根据就诊时的年龄,90例(45%)病例在1岁以下被诊断。充血性心力衰竭(CHF)在ACHD中最为常见,占30%,而在CCHD中只有7%的病例有CHF。这一发现具有统计学意义(p < 0.05)。分析不同CHD的症状,在ACHD和CCHD中,常见症状均为呼吸急促(38%)。

结论 在ACHD患者中,发现31%为VSD,21%为ASD。在CCHD中,TOF最常见,占病例的11.5%。呼吸道疾病是最常见的合并症。由于这是在比哈尔邦儿科年龄组进行的首批研究之一,它有助于了解该地区CHD的患病率,并将有助于利益相关者制定政策。

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