Economides D L, Crook D, Nicolaides K H
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, London, UK.
Fetal Ther. 1988;3(3):165-72. doi: 10.1159/000263349.
Plasma triglyceride, nonesterified fatty acid (NEFA), glycerol, insulin and blood glucose concentrations were measured in 32 small for gestational age (SGA) and 54 appropriate for gestational age fetuses. Although the values of plasma NEFA and glycerol concentrations were not different in the two groups, some SGA fetuses were hypertriglyceridemic, hypoglycemic and hypoinsulinemic. These findings suggest that hypertriglyceridemia in hypoxemic SGA fetuses is not due to lipolysis, nor to increased triglyceride synthesis, but rather to impaired utilization of circulating triglycerides.
对32例小于胎龄儿(SGA)和54例适于胎龄儿的胎儿测量了血浆甘油三酯、非酯化脂肪酸(NEFA)、甘油、胰岛素和血糖浓度。虽然两组的血浆NEFA和甘油浓度值没有差异,但一些SGA胎儿存在高甘油三酯血症、低血糖症和低胰岛素血症。这些发现表明,低氧血症SGA胎儿的高甘油三酯血症不是由于脂肪分解,也不是由于甘油三酯合成增加,而是由于循环甘油三酯的利用受损。