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腺样体扁桃体切除术后持续性阻塞性睡眠呼吸暂停的药物诱导睡眠内镜引导手术的结果

Outcome of drug-induced sleep endoscopy-directed surgery for persistent obstructive sleep apnea after adenotonsillar surgery.

作者信息

Esteller E, Villatoro J C, Agüero A, Matiñó E, Lopez R, Aristimuño A, Nuñez V, Díaz-Herrera M A

机构信息

Otorhinolaryngology Department, Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, Spain; Medicine Department, Universitat Internacional de Catalunya, Sant Cugat del Vallès, Barcelona, Spain.

Otorhinolaryngology Department, Hospital General de Catalunya, Sant Cugat del Vallès, Barcelona, Spain.

出版信息

Int J Pediatr Otorhinolaryngol. 2019 May;120:118-122. doi: 10.1016/j.ijporl.2019.02.004. Epub 2019 Feb 6.

Abstract

PURPOSE

Drug-induced sleep endoscopy (DISE) is suitable for evaluating persistent obstructive sleep apnea syndrome (OSAS) after adenotonsillar surgery as a means to guide surgical intervention, yet few studies demonstrate its usefulness in resolving the syndrome. We describe our experience of DISE-directed surgery in children with persistent OSAS by analysing objective and subjective outcomes of this treatment.

METHODS

Prospective study of 20 otherwise healthy 2-12 year-old children with OSAS persisting after adenotonsillar surgery. All patients underwent DISE-directed surgery and were followed up clinically and with a polysomnogram at 12 ± 3 months.

RESULTS

All 20 children had an apnea-hypopnea index (AHI) score ≥1 (mean: 6.1 ± 4.9) and 75% had AHI>3 before surgery. We performed a total of 14 total tonsillectomies (70%), 7 with associated pharyngoplasties; 5 radiofrequency turbinate reductions (25%); 7 radiofrequency lingual tonsil reductions (35%); and 10 revision adenoidectomies (50%). No surgery-related complications were observed. AHI scores at follow-up were significantly lower than AHI scores before surgery (1.895 ± 1.11 vs 6.143 ± 4.88; p < 0.05) and, in 85% (n = 17) of patients, AHI was below 3. There was a significant reduction in the number of children with AHI>3 in follow-up at 12 ± 3 months (15%; n = 3) compared to before surgery (75%; n = 15) (p < 0.005).

CONCLUSION

DISE-directed surgery for otherwise healthy children with persistent OSAS is a useful and safe technique to decide a therapeutic strategy and to obtain good objective and subjective results regarding resolution of the syndrome.

摘要

目的

药物诱导睡眠内镜检查(DISE)适用于评估腺样体扁桃体切除术后持续性阻塞性睡眠呼吸暂停综合征(OSAS),作为指导手术干预的一种手段,但很少有研究证明其在解决该综合征方面的有用性。我们通过分析这种治疗方法的客观和主观结果,描述我们在持续性OSAS儿童中进行DISE指导手术的经验。

方法

对20名腺样体扁桃体切除术后仍患有OSAS的2至12岁健康儿童进行前瞻性研究。所有患者均接受DISE指导手术,并在12±3个月时进行临床随访和多导睡眠图检查。

结果

所有20名儿童的呼吸暂停低通气指数(AHI)评分≥1(平均:6.1±4.9),75%的儿童术前AHI>3。我们总共进行了14例全扁桃体切除术(70%),其中7例伴有咽成形术;5例射频鼻甲缩小术(25%);7例射频舌扁桃体缩小术(35%);以及10例腺样体切除术(50%)。未观察到与手术相关的并发症。随访时的AHI评分显著低于术前AHI评分(1.895±1.11 vs 6.143±4.88;p<0.05),85%(n=17)的患者AHI低于3。与术前(75%;n=15)相比,在12±3个月的随访中,AHI>3的儿童数量显著减少(15%;n=3)(p<0.005)。

结论

对于患有持续性OSAS的健康儿童,DISE指导手术是一种有用且安全的技术,可用于决定治疗策略并在综合征解决方面获得良好的客观和主观结果。

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