Private Dental Praxis, Stefanstraße 2, 44135, Dortmund, Germany.
University Hospital Münster, Department of Cranio-Maxillofacial Surgery, Waldeyerstraße 30, 48149, Muenster, Germany.
J Craniomaxillofac Surg. 2019 May;47(5):741-749. doi: 10.1016/j.jcms.2019.01.041. Epub 2019 Feb 4.
Patients with cleft lip, alveolus and palate (CLAP) may suffer from marked asymmetry with an impact on attractiveness and psychosocial aspects. The aim of this study was to assess symmetry in CLAP patients compared to non-cleft controls of similar age with regard to cleft type and treatment concept.
In CLAP patients with different cleft forms and in healthy non-cleft subjects (control group) a three-dimensional stereophotogrammetric face scan was performed and an objective 3D asymmetry index (AI) was calculated for the whole face, the midface, the upper lip and the nose.
In total, 305 patients were included: 140 CLAP patients (90 male, 50 female, mean age 9.9 ± 3.6 years) and 165 controls (87 male, 78 female, mean age 8.7 ± 2.1 years). In general, CLAP patients showed significantly higher asymmetry than controls, with the most severe asymmetry found in unilateral complete CLAP. Patients treated according to an actual concept considering reconstruction of all affected muscular systems had a significant lower and more favourable AI than patients not treated according to this concept (p < 0.05).
An adequate treatment concept is essential to achieve better results concerning symmetry in CLAP, but symmetry values of healthy non-cleft controls are not reached.
唇腭裂（CLAP）患者可能存在明显的不对称性，这会影响其美观和社会心理方面。本研究旨在评估不同唇裂类型和治疗方案的 CLAP 患者与相似年龄的非唇裂对照组之间的对称性。
对不同唇裂形式的 CLAP 患者和健康非唇裂受试者（对照组）进行三维立体摄影面部扫描，并计算整个面部、中面部、上唇和鼻子的客观 3D 不对称指数（AI）。
共纳入 305 例患者：140 例 CLAP 患者（90 例男性，50 例女性，平均年龄 9.9 ± 3.6 岁）和 165 例对照组（87 例男性，78 例女性，平均年龄 8.7 ± 2.1 岁）。总体而言，CLAP 患者的不对称性明显高于对照组，单侧完全性 CLAP 患者的不对称性最严重。根据考虑重建所有受累肌肉系统的实际概念进行治疗的患者的 AI 显著低于未按此概念治疗的患者（p < 0.05）。
充分的治疗方案对于 CLAP 患者的对称性至关重要，但无法达到健康非唇裂对照组的对称性。
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