Department of Ocular Tumor, Orbital Disease and Ophthalmic Radiation Therapy, The New York Eye Cancer Center, New York City, New York, USA.
Indian J Ophthalmol. 2019 Mar;67(3):350-357. doi: 10.4103/ijo.IJO_1253_18.
The purpose of this study is to describe the clinical characteristics, multimodality imaging findings, and clinical course of iris varices.
Retrospective, noncomparative, observational case series of 28 eyes of 26 patients with iris varices, diagnosed between 2007 and 2017, has been used.
The mean (±SD) age was 58.3 ± 12.5 years (median 57.5, range 37-81). Patients were 57.7% male and 27% hypertensive. Varices were bilateral in two patients. The mean and median visual acuities were both 20/20 (range 20/16-20/40). Intraocular pressures were 16 mmHg (10-23 mmHg). Secondary glaucoma did not occur. The inferotemporal iris quadrant was affected in 75%. A single varix was seen in 64% and 36% appeared multiple. Varix orientation was radial in 57% and circumferential in 21%. Combined radial and circumferential varix orientation was noted in 18%. One had independent radial and circumferential varices in separate quadrants. A single episcleral sentinel blood vessel directed to the varix was present in 36%. Ultrasound biomicroscopy (UBM) showed a slightly increased mean iris thickness of 0.8 mm and multiple echolucent iris stromal vascular channels. Iris angiography showed no leakage of dye. Managed by observation over a mean follow-up of 37.7 months (range, 3-129), 96.4% eyes were stable and one (3.6%) regressed. No corectopia, ectropion uveae, hyphema, or metachronous anterior segment benign or malignant tumors occurred.
Iris varix is primarily located in the inferotemporal quadrant and not associated with dysmorphic pupillary findings, progression, secondary glaucoma, or malignancy. Iris varices were benign vasculopathies with no associated ocular or vision-related morbidity.
本研究旨在描述虹膜静脉曲张的临床特征、多模态影像学表现和临床病程。
回顾性、非对照、观察性病例系列研究纳入了 2007 年至 2017 年间诊断的 26 例 28 只眼的虹膜静脉曲张患者。
患者的平均(±标准差)年龄为 58.3±12.5 岁(中位数 57.5 岁,范围 37-81 岁)。男性占 57.7%,高血压患者占 27%。两名患者为双眼病变。平均和中位数视力均为 20/20(范围 20/16-20/40)。眼内压为 16mmHg(10-23mmHg)。未发生继发性青光眼。25%的患者为下颞侧虹膜象限受累。单一静脉曲出现于 64%的患者中,36%的患者表现为多发静脉曲。静脉曲的方向为放射状占 57%,环形占 21%。18%的患者同时存在放射状和环形静脉曲。1 例患者在不同象限分别存在独立的放射状和环形静脉曲。36%的患者存在单一的巩膜哨兵血管指向静脉曲。超声生物显微镜(UBM)显示虹膜平均厚度略有增加,为 0.8mm,多个虹膜基质血管通道呈弱回声。虹膜血管造影未见染料渗漏。在平均 37.7 个月(范围 3-129 个月)的随访中,通过观察进行管理,96.4%的眼稳定,1 眼(3.6%)退化。未发生瞳孔异位、葡萄膜外翻、前房积血或异时性前节良性或恶性肿瘤。
虹膜静脉曲张主要位于下颞象限,与瞳孔形态异常、进展、继发性青光眼或恶性肿瘤无关。虹膜静脉曲张是良性血管病变,无相关眼部或视力相关的发病率。