Shri Bhagwan Mahavir Vitreoretinal Services, Sankara Nethralaya, 18 College Road, Chennai, Tamil Nadu, India.
Indian J Ophthalmol. 2019 Mar;67(3):417-419. doi: 10.4103/ijo.IJO_1249_18.
Paracentral acute middle maculopathy (PAMM) refers to retinal lesions with changes in the inner nuclear layer on spectral domain optical coherence tomography (OCT). PAMM is associated with retinal vascular pathology involving the deep capillary plexus. We report two cases of PAMM in Indian subjects using multimodal imaging highlighting the OCT angiography (OCTA) findings. The first case is of a middle-aged female with a paracentral scotoma with SS-OCT (swept-source optical coherence tomography) and OCTA findings suggestive of "chronic" PAMM. The second case presented with sudden decreased vision, and multiple creamy white lesions suggestive of "acute" PAMM, imaging features depicting a possible venular obstruction. These cases demonstrate the importance of considering PAMM as a differential diagnosis in patient presenting with nonspecific visual complains and apparently normal ophthalmic examination. The recognition of PAMM should prompt an appropriate evaluation and investigation.
旁中心急性中黄斑病变(PAMM)是指在频域光相干断层扫描(OCT)上出现内核层改变的视网膜病变。PAMM 与涉及深层毛细血管丛的视网膜血管病变有关。我们使用多模态成像报告了两例印度患者的 PAMM,突出了 OCT 血管造影(OCTA)的发现。第一个病例是一名中年女性,有旁中心暗点,SS-OCT(扫频源光学相干断层扫描)和 OCTA 发现提示“慢性”PAMM。第二个病例表现为突然视力下降,多个奶油色白色病灶提示“急性”PAMM,影像学特征提示可能存在静脉阻塞。这些病例表明,在出现非特异性视觉主诉和明显正常眼科检查的患者中,考虑 PAMM 作为鉴别诊断的重要性。认识到 PAMM 应该促使进行适当的评估和调查。