宫内生长受限新生儿的心脏左心形态和功能：对长期评估的意义
Cardiac left heart morphology and function in newborns with intrauterine growth restriction: relevance for long-term assessment.
作者信息
Zaharie Gabriela Corina, Hasmasanu Monica, Blaga Ligia, Matyas Melinda, Muresan Daniel, Bolboaca Sorana Daniela
机构信息
Neonatology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy.
Obstetrics and Gynecology department, Cluj Napoca, Romania Iuliu Hatieganu University of Medicine and Pharmacy.
出版信息
Med Ultrason. 2019 Feb 17;21(1):62-68. doi: 10.11152/mu-1667.
AIM
To asses the cardiac morphology and functional changes specific for newborns from intrauterine growth restriction (IUGR) pregnancies.
MATERIAL AND METHOD
A cohort of IUGR infants were evaluated by serial echocardiographies at delivery and at the first and six months follow-ups. IUGR newborn delivery status was compared to that of newborns in the control group according to gestational age (AGA).
RESULTS
Left heart measurements were significantly lower in IUGR newborns compared to AGA babies. Left ventricular size increased at follow-up inthe IUGR group (p<0.05). Systolic dysfunction (the myocardial performance index (MPI)> 0.47) was identified in 40% of the neonates in the IUGR group (16/40), respectively 4.76% in the control group. IUGR neonates had a significantly increased proportion of systolic malfunction (p=0.004).
CONCLUSION
IUGR patients had reduced left ventricle dimensions compared to AGA babies. The MPI stands out as a marker of leftheart function in newborns. Systolic dysfunction was a hallmark of the cardiac adaptation in IUGR neonates.
目的
评估宫内生长受限（IUGR）妊娠新生儿特有的心脏形态和功能变化。
材料与方法
对一组IUGR婴儿在分娩时、出生后1个月和6个月随访时进行系列超声心动图检查。根据胎龄（AGA）将IUGR新生儿的分娩情况与对照组新生儿进行比较。
结果
与AGA婴儿相比，IUGR新生儿的左心测量值显著降低。IUGR组随访时左心室大小增加（p<0.05）。IUGR组40%（16/40）的新生儿出现收缩功能障碍（心肌性能指数（MPI）>0.47），对照组为4.76%。IUGR新生儿收缩功能障碍的比例显著增加（p=0.004）。
结论
与AGA婴儿相比，IUGR患者的左心室尺寸减小。MPI是新生儿左心功能的一个标志物。收缩功能障碍是IUGR新生儿心脏适应的一个标志。
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