Guarro J, Figueras J, Cano J
Departamento de Biología y Microbiología, Facultad de Medicina, Universidad de Barcelona.
Microbiologia. 1988 Feb;4(1):29-37.
The degradation "in vitro" of human hair, invaded by the dermatophyte Trichophyton mentagrophytes was studied by means of scanning and transmission electron microscopy. The digestion of the hair started as well in the cuticle as in the cortex, in the regions with low content of keratin, especially in the intercellular spaces. The exocuticle and epicuticle were the most resistant parts of the cuticle in fungal degradation, due to its high content in cystine. In the cortex the macrofibrils were first separated from each other and later attacked on the surface and the interior, arriving to be almost completely degraded. At the end only pigmented granules and rests of membranes could be observed. After a month the hair was almost entirely destroyed probably due to an enzymatic process although some mechanical alteration could also be observed.
通过扫描电子显微镜和透射电子显微镜研究了须癣毛癣菌侵入后人类毛发在“体外”的降解情况。毛发的消化在角质层含量低的区域，尤其是细胞间隙，在角质层和皮质中均开始。由于其胱氨酸含量高，外角质层和上表皮是真菌降解中角质层最具抗性的部分。在皮质中，大纤维首先彼此分离，随后其表面和内部受到攻击，最终几乎完全降解。最后只能观察到色素颗粒和膜的残余物。一个月后，毛发几乎完全被破坏，这可能是由于酶促过程，尽管也可观察到一些机械改变。
