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须癣毛癣菌和红色毛癣菌所致体外实验性毛发感染的超微结构研究

Ultrastructural studies on experimental hair infections in vitro caused by Trichophyton mentagrophytes and Trichophyton rubrum.

作者信息

Kaaman T, Forslind B

出版信息

Acta Derm Venereol. 1985;65(6):536-9.

PMID:2420120
Abstract

Experimental infections with Trichophyton mentagrophytes and Trichophyton rubrum were performed on human hair in vitro and studied by conventional light microscopy, scanning (SEM) and transmission (TEM) electron microscopy. The penetrations visible by light microscopy in hair infected with T. mentagrophytes appeared at SEM as disrupted surface areas with perforating holes. T. rubrum-infected hair displayed minute perforations and less conspicuous cuticular damages seen at SEM and TEM. In both organisms multiple tiny perforating holes were observed at SEM previously unnoticed in experimental hair infections. From a morphological point of view the differences between the fungi investigated in this experimental system seem to be more of a quantitative nature than involving different mechanisms of action.

摘要

用须癣毛癣菌和红色毛癣菌对人毛发进行体外实验性感染,并通过传统光学显微镜、扫描电子显微镜(SEM)和透射电子显微镜(TEM)进行研究。光学显微镜下在感染须癣毛癣菌的毛发中可见的侵入部位,在扫描电子显微镜下表现为带有穿孔的表面破坏区域。感染红色毛癣菌的毛发在扫描电子显微镜和透射电子显微镜下显示出微小的穿孔和不太明显的角质层损伤。在这两种真菌中,扫描电子显微镜观察到多个微小穿孔,这些穿孔在实验性毛发感染中以前未被注意到。从形态学角度来看,该实验系统中所研究真菌之间的差异似乎更多是数量上的,而非涉及不同的作用机制。

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