• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

与英国和威尔士接受月经过多手术治疗相关的因素:国家重度月经过多审计队列研究的结果。

Factors associated with receiving surgical treatment for menorrhagia in England and Wales: findings from a cohort study of the National Heavy Menstrual Bleeding Audit.

机构信息

Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK.

Lindsay Stewart Centre for Audit and Clinical Informatics, Royal College of Obstetricians and Gynaecologists, London, UK.

出版信息

BMJ Open. 2019 Feb 19;9(2):e024260. doi: 10.1136/bmjopen-2018-024260.

DOI:10.1136/bmjopen-2018-024260
PMID:30782899
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6377553/
Abstract

OBJECTIVE

To examine the factors associated with receiving surgery for heavy menstrual bleeding (HMB) in England and Wales.

DESIGN

National cohort study.

SETTING

National Health Service hospitals.

PARTICIPANTS

Women with HMB aged 18-60 who had a new referral to secondary care.

METHODS

Patient-reported data linked to administrative hospital data. Risk ratios (RR) estimated using multivariable Poisson regression.

PRIMARY OUTCOME MEASURE

Surgery within 1 year of first outpatient clinic visit.

RESULTS

14 545 women were included. At their first clinic visit, mean age was 42 years, mean symptom severity score was 62 (scale ranging from 0 (least) to 100 (most severe)), 73.9% of women reported having symptoms for >1 year and 30.4% reported no prior treatment in primary care. One year later, 42.6% had received surgery. Of these, 57.8% had endometrial ablation and 37.2% hysterectomy. Women with more severe symptoms were more likely to have received surgery (most vs least severe quintile, 33.1% vs 56.0%; RR 1.6, 95% CI 1.5 to 1.7). Surgery was more likely among those who reported prior primary care treatment compared with those who did not (48.0% vs 31.1%; RR 1.5, 95% CI 1.4 to 1.6). Surgery was less likely among Asian and more likely among black women, compared with white women. Surgery was not associated with socioeconomic deprivation.

CONCLUSIONS

Receipt of surgery for HMB depends on symptom severity and prior treatment in primary care. Referral pathways should be locally audited to ensure women with HMB receive care that addresses their individual needs and preferences, especially for those who do not receive treatment in primary care.

摘要

目的

探讨英格兰和威尔士女性接受重度月经过多(HMB)手术的相关因素。

设计

全国队列研究。

设置

国民保健制度医院。

参与者

年龄在 18-60 岁之间、因 HMB 而首次转诊至二级保健的女性。

方法

患者报告数据与医院行政数据相关联。采用多变量泊松回归估计风险比(RR)。

主要结局测量

首次门诊就诊后 1 年内接受手术。

结果

共纳入 14545 名女性。在首次就诊时,平均年龄为 42 岁,平均症状严重程度评分为 62 分(0 分表示症状最轻,100 分表示症状最重),73.9%的女性报告症状持续时间超过 1 年,30.4%的女性在初级保健中未接受过治疗。一年后,42.6%的患者接受了手术。其中,57.8%接受了子宫内膜消融术,37.2%接受了子宫切除术。症状更严重的女性更有可能接受手术(最严重与最不严重五分位数组相比,33.1%比 56.0%;RR 1.6,95%置信区间 1.5 至 1.7)。与未接受治疗的患者相比,报告先前接受过初级保健治疗的患者更有可能接受手术(48.0%比 31.1%;RR 1.5,95%置信区间 1.4 至 1.6)。与白人女性相比,亚洲女性接受手术的可能性较小,而黑人女性则更有可能接受手术。手术与社会经济贫困程度无关。

结论

HMB 手术的接受程度取决于症状严重程度和初级保健中的治疗情况。应在当地审核转诊途径,以确保 HMB 患者获得符合其个体需求和偏好的治疗,特别是对那些未在初级保健中接受治疗的患者。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/6377553/01cd0ac48b2e/bmjopen-2018-024260f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/6377553/01cd0ac48b2e/bmjopen-2018-024260f01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20ca/6377553/01cd0ac48b2e/bmjopen-2018-024260f01.jpg

相似文献

1
Factors associated with receiving surgical treatment for menorrhagia in England and Wales: findings from a cohort study of the National Heavy Menstrual Bleeding Audit.与英国和威尔士接受月经过多手术治疗相关的因素:国家重度月经过多审计队列研究的结果。
BMJ Open. 2019 Feb 19;9(2):e024260. doi: 10.1136/bmjopen-2018-024260.
2
Sociodemographic differences in symptom severity and duration among women referred to secondary care for menorrhagia in England and Wales: a cohort study from the National Heavy Menstrual Bleeding Audit.英格兰和威尔士因月经过多转诊至二级医疗机构的女性在症状严重程度和持续时间上的社会人口学差异:一项来自国家严重月经出血审计的队列研究
BMJ Open. 2018 Feb 2;8(2):e018444. doi: 10.1136/bmjopen-2017-018444.
3
Rates of subsequent surgery following endometrial ablation among English women with menorrhagia: population-based cohort study.英国月经过多女性行子宫内膜消融术后再次手术的比率:基于人群的队列研究。
BJOG. 2013 Nov;120(12):1500-7. doi: 10.1111/1471-0528.12319. Epub 2013 Jun 21.
4
Association Between Patient Characteristics and Treatment Procedure Among Patients With Uterine Leiomyomas.子宫肌瘤患者的患者特征与治疗程序之间的关联
Obstet Gynecol. 2016 Jan;127(1):67-77. doi: 10.1097/AOG.0000000000001160.
5
Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding.子宫内膜切除术和消融术与子宫切除术治疗月经过多的比较
Cochrane Database Syst Rev. 2013 Nov 29(11):CD000329. doi: 10.1002/14651858.CD000329.pub2.
6
Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding.子宫内膜切除术和消融术与子宫切除术治疗月经过多的比较
Cochrane Database Syst Rev. 2019 Aug 29;8(8):CD000329. doi: 10.1002/14651858.CD000329.pub3.
7
Laparoscopic supracervical hysterectomy compared with second-generation endometrial ablation for heavy menstrual bleeding: the HEALTH RCT.腹腔镜下子宫颈以上切除术与第二代子宫内膜消融术治疗月经过多的比较:HEALTH RCT。
Health Technol Assess. 2019 Sep;23(53):1-108. doi: 10.3310/hta23530.
8
Surgical treatment of fibroids in heavy menstrual bleeding.月经过多的子宫肌瘤手术治疗。
Womens Health (Lond). 2016 Jan;12(1):53-62. doi: 10.2217/whe.15.89. Epub 2015 Dec 23.
9
Comparative Effectiveness of Uterine Leiomyoma Procedures Using a Large Insurance Claims Database.利用大型保险理赔数据库比较子宫肌瘤手术的疗效
Obstet Gynecol. 2017 Nov;130(5):1047-1056. doi: 10.1097/AOG.0000000000002331.
10
Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding.子宫内膜切除术和消融术与子宫切除术治疗月经过多。
Cochrane Database Syst Rev. 2021 Feb 23;2(2):CD000329. doi: 10.1002/14651858.CD000329.pub4.

引用本文的文献

1
Prevalence and risk factors of heavy menstrual bleeding in Africa: a narrative review.非洲月经过多的患病率及危险因素:一项叙述性综述。
Ann Med Surg (Lond). 2025 May 20;87(7):4194-4200. doi: 10.1097/MS9.0000000000003394. eCollection 2025 Jul.
2
Treatment options for women with heavy menstrual bleeding: a protocol for comprehensive systematic review, network meta-analyses and health economic assessment.月经过多女性的治疗选择:一项全面系统评价、网状荟萃分析和卫生经济评估方案
BMJ Open. 2025 Apr 22;15(4):e085292. doi: 10.1136/bmjopen-2024-085292.
3
Measurement of changes in uterine and fibroid volume during treatment of heavy menstrual bleeding (HMB).

本文引用的文献

1
Sociodemographic differences in symptom severity and duration among women referred to secondary care for menorrhagia in England and Wales: a cohort study from the National Heavy Menstrual Bleeding Audit.英格兰和威尔士因月经过多转诊至二级医疗机构的女性在症状严重程度和持续时间上的社会人口学差异:一项来自国家严重月经出血审计的队列研究
BMJ Open. 2018 Feb 2;8(2):e018444. doi: 10.1136/bmjopen-2017-018444.
2
Epidemiology of Uterine Fibroids: From Menarche to Menopause.子宫肌瘤的流行病学:从初潮到绝经
Clin Obstet Gynecol. 2016 Mar;59(1):2-24. doi: 10.1097/GRF.0000000000000164.
3
The delivery of heavy menstrual bleeding services in England and Wales after publication of national guidelines: a survey of hospitals.
月经过多(HMB)治疗期间子宫及肌瘤体积变化的测量。
Hum Reprod Open. 2023 May 22;2023(3):hoad021. doi: 10.1093/hropen/hoad021. eCollection 2023.
4
An update on uterine artery embolization for uterine leiomyomata and adenomyosis of the uterus.子宫动脉栓塞术治疗子宫肌瘤和子宫腺肌病的最新进展。
Br J Radiol. 2023 Mar;96(1143):20220121. doi: 10.1259/bjr.20220121. Epub 2022 Nov 25.
5
Interventions to improve access to care for abnormal uterine bleeding: A systematic scoping review.改善异常子宫出血患者获得护理的干预措施:系统范围界定审查。
Int J Gynaecol Obstet. 2023 Jan;160(1):38-48. doi: 10.1002/ijgo.14224. Epub 2022 May 5.
6
Endometrial resection and ablation versus hysterectomy for heavy menstrual bleeding.子宫内膜切除术和消融术与子宫切除术治疗月经过多。
Cochrane Database Syst Rev. 2021 Feb 23;2(2):CD000329. doi: 10.1002/14651858.CD000329.pub4.
7
Unnecessary hysterectomies and our role as interventional radiology community.不必要的子宫切除术以及我们介入放射学界的作用。
CVIR Endovasc. 2020 Jul 14;3(1):46. doi: 10.1186/s42155-020-00138-x.
8
90 YEARS OF PROGESTERONE: Selective progesterone receptor modulators in gynaecological therapies.90 年的孕激素:妇科治疗中的选择性孕激素受体调节剂。
J Mol Endocrinol. 2020 Jul;65(1):T15-T33. doi: 10.1530/JME-19-0238.
9
Geographical variation in rates of surgical treatment for female stress urinary incontinence in England: a national cohort study.英格兰女性压力性尿失禁手术治疗率的地理差异:一项全国队列研究。
BMJ Open. 2019 Aug 28;9(8):e029878. doi: 10.1136/bmjopen-2019-029878.
英国和威尔士全国性指南发布后,对重度月经过多服务的提供情况的调查:医院调查。
BMC Health Serv Res. 2013 Nov 25;13:491. doi: 10.1186/1472-6963-13-491.
4
Endometrial resection and ablation techniques for heavy menstrual bleeding.用于治疗月经过多的子宫内膜切除术和消融技术。
Cochrane Database Syst Rev. 2013 Aug 30(8):CD001501. doi: 10.1002/14651858.CD001501.pub4.
5
Rates of subsequent surgery following endometrial ablation among English women with menorrhagia: population-based cohort study.英国月经过多女性行子宫内膜消融术后再次手术的比率:基于人群的队列研究。
BJOG. 2013 Nov;120(12):1500-7. doi: 10.1111/1471-0528.12319. Epub 2013 Jun 21.
6
Overestimation of risk ratios by odds ratios in trials and cohort studies: alternatives to logistic regression.在试验和队列研究中,比值比对比值比的风险比高估:逻辑回归的替代方法。
CMAJ. 2012 May 15;184(8):895-9. doi: 10.1503/cmaj.101715. Epub 2011 Dec 12.
7
Hysterectomy, endometrial ablation and Mirena® for heavy menstrual bleeding: a systematic review of clinical effectiveness and cost-effectiveness analysis.子宫切除术、子宫内膜消融术和 Mirena®治疗月经过多:临床有效性和成本效益分析的系统评价。
Health Technol Assess. 2011 Apr;15(19):iii-xvi, 1-252. doi: 10.3310/hta15190.
8
Population based time trends and socioeconomic variation in use of radiotherapy and radical surgery for prostate cancer in a UK region: continuous survey.基于人群的时间趋势和英国某地区前列腺癌放疗和根治性手术使用的社会经济变化:连续调查。
BMJ. 2010 Apr 21;340:c1928. doi: 10.1136/bmj.c1928.
9
Surgery for menorrhagia within English regions: variation in rates of endometrial ablation and hysterectomy.英国各地区月经过多的手术治疗:子宫内膜去除术和子宫切除术的比率差异
BJOG. 2009 Sep;116(10):1373-9. doi: 10.1111/j.1471-0528.2009.02284.x. Epub 2009 Jul 28.
10
Endometrial ablation in England--coming of age? An examination of hospital episode statistics 1989/1990 to 2004/2005.英国的子宫内膜去除术——走向成熟了吗?对1989/1990年至2004/2005年医院诊疗统计数据的研究
Eur J Obstet Gynecol Reprod Biol. 2007 Dec;135(2):191-4. doi: 10.1016/j.ejogrb.2006.08.008. Epub 2006 Oct 12.