以手臂悬浮为首发表现的克雅氏病：病例报告及文献复习
Arm Levitation as Initial Manifestation of Creutzfeldt-Jakob Disease: Case Report and Review of the Literature.
作者信息
Ciarlariello Vinícius Boaratti, Barsottini Orlando G P, Espay Alberto J, Pedroso José Luiz
机构信息
Department of Neurology, Hospital Israelita Albert Einstein, São Paulo, SP, Brazil.
Department of Neurology, Ataxia Unit, Universidade Federal de São Paulo, São Paulo, SP, Brazil.
出版信息
Tremor Other Hyperkinet Mov (N Y). 2018 Dec 10;8:572. doi: 10.7916/D80C6CGX. eCollection 2018.
BACKGROUND
Arm levitation is an involuntary elevation of the upper limb, a manifestation of the alien-limb phenomenon. It has rarely been reported in Creutzfeldt-Jakob disease (CJD), less so as an initial manifestation.
CASE REPORT
We report a 56-year-old right-handed man with rapidly progressive gait ataxia and involuntary elevation of the left upper limb. During the next few weeks, the patient developed cognitive impairment, apraxia, visual hallucinations, and myoclonus. He met diagnostic criteria for CJD. We evaluated additional published cases of early-appearance of alien-limb phenomenon in the context of CJD; there were 22 such cases and alien-limb phenomenon was the first and exclusive manifestation in only five of them.
DISCUSSION
Arm levitation may be a distinct presentation of CJD, appearing earlier than other clinical features.
背景
上肢漂浮是上肢的一种不自主抬起，是异己肢体现象的一种表现。在克雅氏病（CJD）中鲜有报道，作为首发表现则更为罕见。
病例报告
我们报告一名56岁右利手男性，出现快速进展的步态共济失调和左上肢不自主抬起。在接下来的几周内，患者出现认知障碍、失用症、视幻觉和肌阵挛。他符合CJD的诊断标准。我们评估了已发表的CJD背景下异己肢体现象早期出现的其他病例；共有22例此类病例，其中仅5例异己肢体现象是首发且唯一的表现。
讨论
上肢漂浮可能是CJD的一种独特表现，比其他临床特征出现更早。
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