Ohtsuka H
Department of Dermatology (Section of Plastic and Reconstructive Surgery), Ehime University School of Medicine, Japan.
Ann Plast Surg. 1986 Aug;17(2):155-60. doi: 10.1097/00000637-198608000-00011.
A girl manifesting a false median cleft lip associated with hypertelorism, anophthalmos, hydranencephaly with holoprosencephaly, and osteogenesis imperfecta, among other disorders, survived and was fed mainly milk products up to the age of 11. Then, surgical closure of the false median cleft lip was undertaken to improve the face aesthetically and to make the child more acceptable to society at large. The patient's median cerebrofacial dysgenesis with other anomalies was unique, compared with disorders reported in the literature. The embryological distinction between a false and true median cleft lip is also discussed.
一名患有假正中唇裂并伴有眼距过宽、无眼畸形、无脑叶积水合并全前脑畸形以及成骨不全等多种病症的女孩存活了下来，在11岁之前主要以奶制品为食。随后，为改善面部美观并使孩子更能被社会大众接受，对假正中唇裂进行了手术修复。与文献报道的病症相比，该患者的正中脑面发育不全合并其他异常情况较为独特。文中还讨论了假正中唇裂与真正中唇裂在胚胎学上的区别。
