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本文引用的文献

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Incidental focal colonic uptake in studies F-FDG PET/CT.在F-FDG PET/CT研究中偶然发现的局灶性结肠摄取。
Rev Esp Med Nucl Imagen Mol (Engl Ed). 2018 Jan-Feb;37(1):15-19. doi: 10.1016/j.remn.2017.03.012. Epub 2017 Jul 24.
2
Clinical significance of incidental [18 F]FDG uptake in the gastrointestinal tract on PET/CT imaging: a retrospective cohort study.PET/CT成像中胃肠道偶然[18F]FDG摄取的临床意义:一项回顾性队列研究。
BMC Gastroenterol. 2016 Oct 6;16(1):125. doi: 10.1186/s12876-016-0545-x.
3
Accuracy of FDG-PET/CT for Detection of Incidental Pre-Malignant and Malignant Colonic Lesions - Correlation with Colonoscopic and Histopathologic Findings.FDG-PET/CT检测结肠偶发癌前病变和恶性病变的准确性——与结肠镜检查及组织病理学结果的相关性
Asian Pac J Cancer Prev. 2016;17(8):4143-7.
4
Incidental gastrointestinal 18F-Fluorodeoxyglucose uptake associated with lung cancer.与肺癌相关的偶然胃肠道18F-氟脱氧葡萄糖摄取
BMC Pulm Med. 2015 Dec 2;15:152. doi: 10.1186/s12890-015-0152-6.
5
Suture Granuloma With False-Positive Findings on FDG-PET/CT Resected via Laparoscopic Surgery.经腹腔镜手术切除的缝线肉芽肿在FDG-PET/CT上有假阳性表现
Int Surg. 2015 Apr;100(4):604-7. doi: 10.9738/INTSURG-D-14-00140.1.
6
An FDG-PET/CT-positive lesion mimicking local recurrence of colon cancer 5 years after radical colectomy.一例在根治性结肠切除术后5年出现的FDG-PET/CT阳性病变,酷似结肠癌局部复发。
Am J Case Rep. 2015 Mar 12;16:149-52. doi: 10.12659/AJCR.891129.
7
Prevalence and malignancy risk of focal colorectal incidental uptake detected by (18)F-FDG-PET or PET/CT: a meta-analysis.(18)F-FDG-PET 或 PET/CT 检测到的结直肠偶然摄取的流行率和恶性风险:一项荟萃分析。
Radiol Oncol. 2014 Apr 25;48(2):99-104. doi: 10.2478/raon-2013-0035. eCollection 2014 Jun.
8
Observer variation study of the assessment and diagnosis of incidental colonic FDG uptake.偶然发现的结肠 FDG 摄取的评估和诊断的观察者变异研究。
Ann Nucl Med. 2013 Jun;27(5):468-77. doi: 10.1007/s12149-013-0712-x. Epub 2013 Mar 17.
9
The Use of PET-CT in the Assessment of Patients with Colorectal Carcinoma.PET-CT在结直肠癌患者评估中的应用。
Int J Surg Oncol. 2011;2011:846512. doi: 10.1155/2011/846512. Epub 2011 Jul 3.
10
The segmental distribution and clinical significance of colorectal fluorodeoxyglucose uptake incidentally detected on PET-CT.PET-CT偶然发现的结直肠氟脱氧葡萄糖摄取的节段性分布及临床意义。
Nucl Med Commun. 2009 May;30(5):333-7. doi: 10.1097/MNM.0b013e32832999fa.

使用氟脱氧葡萄糖正电子发射断层扫描对结直肠异常情况的价值——一项横断面研究。

The value of using fludeoxyglucose positron-emission tomography scan with respect to colorectal abnormalities-a cross-sectional study.

作者信息

Loffeld Ruud J L F, Srbjlin Sandra A

机构信息

Department of Gastroenterology and Nuclear Medicine, Zaans Medisch Centrum, Zaandam, The Netherlands.

出版信息

J Gastrointest Oncol. 2019 Feb;10(1):1-5. doi: 10.21037/jgo.2018.09.03.

DOI:10.21037/jgo.2018.09.03
PMID:30788152
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6351306/
Abstract

BACKGROUND

Fludeoxyglucose positron-emission tomography (FDG-PET) shows colic uptake regularly. Complementary colonoscopy is done. Aim: study the findings of colonoscopy.

METHODS

All consecutive scans in 5 years were studied. Focal FDG uptake in colon and/or rectum were scored as + or ++. Clinical files and endoscopy reports were studied for final diagnosis.

RESULTS

Focal FDG uptake was noted in 173 out of 2,075 scans (8.4%). Focal FDG activity was judged ++ in 73 patients (42.2%) and + in 100 (57.8%). The majority of colorectal cancers scored ++. Patients with ++ activity underwent or had undergone significantly more often a colonoscopy compared with patients with + activity, 82% versus 65% (P=0.02). FDG PET/CT was false positive with respect to polyp(s) or cancer in 13 cases (22%) of ++ FGD activity and in 38 cases of + FDG (P<0.001). In 25 patients a total of 69 polyps were not FDG avid.

CONCLUSIONS

FDG-PET scanning is a useful tool in oncology. However, false-positive and false-negative findings with respect to colonic uptake are present in a significant number of patients. If the clinical condition and the potential prognosis allows the performance of colonoscopy this procedure should be done.

摘要

背景

氟脱氧葡萄糖正电子发射断层扫描(FDG-PET)常显示结肠摄取。需进行结肠镜检查作为补充。目的:研究结肠镜检查的结果。

方法

对5年内所有连续扫描进行研究。结肠和/或直肠的局灶性FDG摄取分为+或++。研究临床档案和内镜报告以得出最终诊断。

结果

在2075次扫描中有173次(8.4%)发现局灶性FDG摄取。73例患者(42.2%)的局灶性FDG活性被判定为++,100例(57.8%)为+。大多数结直肠癌评分为++。与FDG活性为+的患者相比,FDG活性为++的患者接受或已接受结肠镜检查的比例显著更高,分别为82%和65%(P=0.02)。在13例(22%)FDG活性为++的病例和38例FDG活性为+的病例中,FDG PET/CT在息肉或癌症方面出现假阳性(P<0.001)。在25例患者中,共有69个息肉不摄取FDG。

结论

FDG-PET扫描是肿瘤学中的一种有用工具。然而,相当数量的患者在结肠摄取方面存在假阳性和假阴性结果。如果临床情况和潜在预后允许进行结肠镜检查,则应进行该检查。