Shirvani Mohammad, Hosseini Shahla, Maalhagh Merhrnoosh, Afarid Mehrdad, Mirza-Khanlooi Ali, Mohaghegh Sahar
Poostchi Ophthalmology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Shiraz University of Medical Sciences, Shiraz, Iran.
J Ophthalmic Inflamm Infect. 2019 Feb 20;9(1):5. doi: 10.1186/s12348-019-0172-0.
To report a case of endogenous Candida endophthalmitis that may cause catastrophic sight-threatening outcomes, after extracorporeal shock wave lithotripsy (ESWL) in a healthy woman.
A 32-year-old woman presented to the ophthalmology clinic with the symptom of blurred vision and floater in her right eye. She underwent ESWL for renal stone 1 week prior to her presentation. Fundus examination showed an elevated white lesion in para-fovea with fluffy border. Smear of diagnostic vitreous sampling showed pseudo-hypha and budding yeast. Systemic and immunologic and infectious workups were unremarkable. In our case, response to intravitreal and intravenous injection of amphotericin-B and oral fluconazole was dramatic. Six weeks after starting the treatment, infiltrative lesion completely disappeared. The authors review previous MEDLINE literature about this topic.
Endogenous Candida endophthalmitis following renal stone lithotripsy is a serious and rare intraocular infection that may happen in healthy individuals without any risk factors.
报告一例健康女性在体外冲击波碎石术（ESWL）后发生的内源性念珠菌性眼内炎病例，该病例可能导致灾难性的视力威胁后果。
一名32岁女性因右眼视力模糊和有飞蚊症症状就诊于眼科门诊。她在就诊前1周因肾结石接受了ESWL治疗。眼底检查显示在黄斑旁有一个边界模糊的白色隆起病变。诊断性玻璃体取样涂片显示有假菌丝和出芽酵母。全身、免疫和感染方面的检查均无异常。在我们的病例中，玻璃体腔和静脉注射两性霉素B以及口服氟康唑的治疗反应显著。开始治疗六周后，浸润性病变完全消失。作者回顾了之前关于该主题的MEDLINE文献。
肾结石碎石术后发生的内源性念珠菌性眼内炎是一种严重且罕见的眼内感染，可能发生在没有任何危险因素的健康个体中。
