[帕米尔高原慢性高原病的患病率及危险因素]

[Prevalence and risk factors of chronic mountain sickness in Pamirs plateau].

作者信息

Yang Sheng-Hong, Li Bin, Gao Liang, Li Nian-Hua

机构信息

Xinjiang Military Command Mountain Sickness Research Institute, Hospital 18 of PLA, Yecheng 844900, China.

出版信息

Zhongguo Ying Yong Sheng Li Xue Za Zhi. 2018 Apr 8;34(4):336-339.

PMID:30788941

Abstract

OBJECTIVE

To investigate the prevalence of chronic mountain sickness (CMS) and its predisposing factors in Pamirs plateau and analysis clinical feature and risk factors.

METHODS

Eight hundred and twenty-four individuals in Pamirs plateau were surveyed used Qinghai CMS scoring system. Demographics, BP, SaO, heart rate and specified symptoms of CMS were recorded, Hb level was estimated.

RESULTS

Overall CMS prevalence was 22.08%, including 21.84% mild and 0.24% moderate without severe patient. Gender, nation, age, immigration time, altitude, occupation and accommodation mode were risk factors for CMS (<0.05 or <0.01), CMS prevalence was higher than HAPC rate both in male and female (χ=90.59 and 44.13, <0.01). Multiple linear regression analysis showed age, BMI, SaO and systolic pressure correlated with CMS (<0.01).

CONCLUSIONS

Chronic mountain sickness prevalence in Pamirs plateau is rather high but high altitude polycythemia prevalence is low, so the disease type is high altitude deterioration. Work and exercise more reasonable to avoid overtiredness, oxygen inhalation to raise blood oxygen saturation, control blood pressure and resting therapy can improve CMS symptom and decrease prevalence.

摘要

目的

调查帕米尔高原慢性高原病（CMS）的患病率及其易感因素，并分析其临床特征和危险因素。

方法

采用青海CMS评分系统对帕米尔高原824人进行调查。记录人口统计学资料、血压、血氧饱和度、心率及CMS的特定症状，估算血红蛋白水平。

结果

CMS总患病率为22.08%，其中轻度为21.84%，中度为0.24%，无重度患者。性别、民族、年龄、移居时间、海拔、职业和居住方式是CMS的危险因素（P<0.05或P<0.01），男性和女性的CMS患病率均高于高原红细胞增多症（HAPC）患病率（χ²=90.59和44.13，P<0.01）。多元线性回归分析显示年龄、体重指数、血氧饱和度和收缩压与CMS相关（P<0.01）。