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[In HPV-associated oropharyngeal cancer, chemoradiotherapy with cisplatin is superior to bioradiotherapy with cetuximab in terms of overall survival].

作者信息

Semrau Sabine

机构信息

Universitäts-Strahlenklinik, Universitätsstraße 27, 91054, Erlangen, Deutschland.

出版信息

Strahlenther Onkol. 2019 May;195(5):447-449. doi: 10.1007/s00066-019-01441-w.

DOI:10.1007/s00066-019-01441-w
PMID:30789992
Abstract
摘要

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1
[In HPV-associated oropharyngeal cancer, chemoradiotherapy with cisplatin is superior to bioradiotherapy with cetuximab in terms of overall survival].在人乳头瘤病毒相关的口咽癌中,就总生存期而言,顺铂同步放化疗优于西妥昔单抗生物放疗。
Strahlenther Onkol. 2019 May;195(5):447-449. doi: 10.1007/s00066-019-01441-w.
2
Cisplatin-based chemoradiotherapy trumps cetuximab-based bioradiotherapy in p16/HPV-positive oropharyngeal cancers.在p16/人乳头瘤病毒(HPV)阳性的口咽癌中,基于顺铂的放化疗优于基于西妥昔单抗的生物放疗。
Eur Arch Otorhinolaryngol. 2019 Jul;276(7):2111-2112. doi: 10.1007/s00405-019-05441-5. Epub 2019 Apr 25.
3
[Radiochemotherapy of HPV-positive oropharyngeal carcinomas: Cisplatin is still to be prioritized].[人乳头瘤病毒阳性口咽癌的放化疗:顺铂仍应优先使用]
Bull Cancer. 2020 Mar;107(3):293-294. doi: 10.1016/j.bulcan.2020.02.002. Epub 2020 Feb 26.
4
Subgroup Analysis According to Human Papillomavirus Status and Tumor Site of a Randomized Phase II Trial Comparing Cetuximab and Cisplatin Combined With Radiation Therapy for Locally Advanced Head and Neck Cancer.一项比较西妥昔单抗联合顺铂与放化疗治疗局部晚期头颈部癌的随机 II 期临床试验中,根据人乳头瘤病毒状态和肿瘤部位的亚组分析。
Int J Radiat Oncol Biol Phys. 2017 Mar 1;97(3):462-472. doi: 10.1016/j.ijrobp.2016.10.011. Epub 2016 Oct 20.
5
Predictors of distant metastasis in human papillomavirus-associated oropharyngeal cancer.人乳头瘤病毒相关口咽癌远处转移的预测因素
Head Neck. 2017 May;39(5):940-946. doi: 10.1002/hed.24711. Epub 2017 Feb 11.
6
Impact of cisplatin dose intensity on human papillomavirus-related and -unrelated locally advanced head and neck squamous cell carcinoma.顺铂剂量强度对人乳头瘤病毒相关和不相关的局部晚期头颈部鳞状细胞癌的影响。
Eur J Cancer. 2016 Nov;67:174-182. doi: 10.1016/j.ejca.2016.08.013. Epub 2016 Sep 24.
7
Concurrent chemoradiotherapy with cisplatin or cetuximab for locally advanced head and neck squamous cell carcinomas: Does human papilloma virus play a role?顺铂或西妥昔单抗同步放化疗用于局部晚期头颈部鳞状细胞癌:人乳头瘤病毒起作用吗?
Oral Oncol. 2016 Aug;59:50-57. doi: 10.1016/j.oraloncology.2016.05.019.
8
Clinical outcomes and prognostic factors in cisplatin versus cetuximab chemoradiation for locally advanced p16 positive oropharyngeal carcinoma.铂类药物对比西妥昔单抗联合放化疗治疗局部晚期 p16 阳性口咽癌的临床疗效及预后因素分析。
Oral Oncol. 2018 Apr;79:9-14. doi: 10.1016/j.oraloncology.2018.02.001. Epub 2018 Feb 12.
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The toxicity and efficacy of concomitant chemoradiotherapy in patients aged 70 years and older with oropharyngeal carcinoma in the intensity-modulated radiotherapy era.在调强放疗时代,70岁及以上口咽癌患者同步放化疗的毒性和疗效。
Cancer. 2017 Apr 15;123(8):1345-1353. doi: 10.1002/cncr.30495. Epub 2016 Dec 16.
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Survival, recurrence and toxicity of HNSCC in comparison of a radiotherapy combination with cisplatin versus cetuximab: a meta-analysis.头颈部鳞状细胞癌放疗联合顺铂与西妥昔单抗对比的生存、复发及毒性:一项荟萃分析
BMC Cancer. 2016 Aug 26;16(1):689. doi: 10.1186/s12885-016-2706-2.

引用本文的文献

1
Multimodal treatment according to the NPC-GPOH trials in adult patients with nasopharyngeal cancer-Analysis based on a single-center experience.多模态治疗成人鼻咽癌 NPC-GPOH 试验-基于单中心经验的分析。
Cancer Rep (Hoboken). 2024 Aug;7(8):e2111. doi: 10.1002/cnr2.2111.

本文引用的文献

1
Induction Chemotherapy Followed by Cetuximab Radiotherapy Is Not Superior to Concurrent Chemoradiotherapy for Head and Neck Carcinomas: Results of the GORTEC 2007-02 Phase III Randomized Trial.诱导化疗后联合西妥昔单抗放疗治疗头颈部癌并不优于同步放化疗:GORTEC 2007-02 III期随机试验结果
J Clin Oncol. 2018 Nov 1;36(31):3077-3083. doi: 10.1200/JCO.2017.76.2591. Epub 2018 Jul 17.
2
Treatment de-escalation for HPV-driven oropharyngeal cancer: Where do we stand?人乳头瘤病毒(HPV)驱动的口咽癌治疗降阶梯:我们目前的状况如何?
Clin Transl Radiat Oncol. 2017 Nov 4;8:4-11. doi: 10.1016/j.ctro.2017.10.005. eCollection 2018 Jan.
3
Induction chemotherapy followed by either chemoradiotherapy or bioradiotherapy for larynx preservation: the TREMPLIN randomized phase II study.
诱导化疗后行放化疗或生物放疗保喉:TREMPLIN 随机 2 期研究。
J Clin Oncol. 2013 Mar 1;31(7):853-9. doi: 10.1200/JCO.2012.42.3988. Epub 2013 Jan 22.
4
Human papillomavirus and survival of patients with oropharyngeal cancer.人乳头瘤病毒与口咽癌患者的生存。
N Engl J Med. 2010 Jul 1;363(1):24-35. doi: 10.1056/NEJMoa0912217. Epub 2010 Jun 7.