早期使用PEPA透析器清除轻链及治疗骨髓瘤管型肾病的恢复情况：一例报告
Early use of PEPA dialyzer for light chains removal and for the recovery from myeloma cast nephropathy: A case report.
作者信息
Donati Gabriele, Zappulo Fulvia, Croci Chiocchini Anna Laura, Comai Giorgia, Zamagni Elena, La Manna Gaetano
机构信息
Nephrology Dialysis and Renal Transplantation Unit, L. & A. Seràgnoli, S.Orsola University Hospital, Bologna, Italy.
Hematology and Oncology Unit, L. & A. Seràgnoli, S.Orsola University Hospital, Bologna, Italy.
出版信息
Hemodial Int. 2019 Jul;23(3):E97-E99. doi: 10.1111/hdi.12733. Epub 2019 Feb 21.
Chemotherapy and extracorporeal treatment reduce serum free light chains (FLCs) allowing the recovery of acute kidney injury (AKI) caused by myeloma cast nephropathy (MCN). We report the first case of recovery from AKI in a patient with MCN who underwent the removal of FLCs using the PEPA filter, with an undisclosed cut-off, combined with chemotherapy for multiple myeloma (MM).
化疗和体外治疗可降低血清游离轻链（FLC）水平，从而使由骨髓瘤管型肾病（MCN）引起的急性肾损伤（AKI）得以恢复。我们报告了首例MCN患者AKI恢复的病例，该患者使用未公开截留值的PEPA滤器清除FLC，并联合进行多发性骨髓瘤（MM）化疗。
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