细菌性痢疾发病机制的分子遗传学研究方法
Molecular genetic approaches to the pathogenesis of bacillary dysentery.
作者信息
Yoshikawa M, Sasakawa C, Makino S, Okada N, Lett M C, Sakai T, Yamada M, Komatsu K, Kamata K, Kurata T
机构信息
Institute of Medical Science, University of Tokyo, Japan.
出版信息
Microbiol Sci. 1988 Nov;5(11):333-4, 339.
PMID:3079174
Abstract
Bacillary dysentery is an invasive infectious disease of the human colon. At least three genetic loci on the chromosome and a huge plasmid have been implicated in its pathogenesis. Results obtained from molecular genetic studies, mainly of the genes, virG, virF and kcpA are discussed.
摘要
细菌性痢疾是人类结肠的一种侵袭性传染病。其发病机制涉及染色体上至少三个基因位点和一个巨大的质粒。本文讨论了主要来自virG、virF和kcpA基因的分子遗传学研究结果。
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引用本文的文献
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Genetic basis of virulence in Shigella species.志贺氏菌属毒力的遗传基础。
Microbiol Rev. 1991 Jun;55(2):206-24. doi: 10.1128/mr.55.2.206-224.1991.
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