HuR在表没食子儿茶素-3-没食子酸酯（EGCG）诱导肿瘤细胞凋亡中的新作用。 - Suppr

A novel role of HuR in -Epigallocatechin-3-gallate (EGCG) induces tumour cells apoptosis.

作者信息

Jian Wenxuan, Fang Shuhuan, Chen Tongkai, Fang Jiansong, Mo Yousheng, Li Dongli, Xiong Sha, Liu Wei, Song Lei, Shen Jiangang, Xia Yong, Wang Qi, Hong Honghai

机构信息

DME Center, Institute of Clinical Pharmacology, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong Province, China.

School of Chinese Medicine, The University of Hong Kong, Pokfulam, Hong Kong, China.

出版信息

J Cell Mol Med. 2019 May;23(5):3767-3771. doi: 10.1111/jcmm.14249. Epub 2019 Feb 22.

DOI:10.1111/jcmm.14249

PMID:30793483

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6484420/

Abstract

摘要

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A novel role of HuR in -Epigallocatechin-3-gallate (EGCG) induces tumour cells apoptosis.HuR在表没食子儿茶素-3-没食子酸酯（EGCG）诱导肿瘤细胞凋亡中的新作用。

J Cell Mol Med. 2019 May;23(5):3767-3771. doi: 10.1111/jcmm.14249. Epub 2019 Feb 22.

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本文引用的文献

The amyloid precursor protein (APP) processing as a biological link between Alzheimer's disease and cancer.淀粉样前体蛋白 (APP) 处理作为阿尔茨海默病和癌症之间的生物学联系。

Ageing Res Rev. 2019 Jan;49:83-91. doi: 10.1016/j.arr.2018.11.007. Epub 2018 Nov 27.

The physical approximation of APP and BACE-1: A key event in alzheimer's disease pathogenesis.淀粉样前体蛋白（APP）和 BACE-1 的物理近似：阿尔茨海默病发病机制中的关键事件。

Dev Neurobiol. 2018 Mar;78(3):340-347. doi: 10.1002/dneu.22556. Epub 2017 Nov 13.

Green Tea Extracts Epigallocatechin-3-gallate for Different Treatments.绿茶提取物表没食子儿茶素没食子酸酯用于不同的治疗。

Biomed Res Int. 2017;2017:5615647. doi: 10.1155/2017/5615647. Epub 2017 Aug 13.

Activation of Ras-ERK Signaling and GSK-3 by Amyloid Precursor Protein and Amyloid Beta Facilitates Neurodegeneration in Alzheimer's Disease.淀粉样前体蛋白和淀粉样 β 通过激活 Ras-ERK 信号通路和 GSK-3 促进阿尔茨海默病中的神经退行性变。

eNeuro. 2017 Mar 27;4(2). doi: 10.1523/ENEURO.0149-16.2017. eCollection 2017 Mar-Apr.

Not just amyloid: physiological functions of the amyloid precursor protein family.不仅是淀粉样蛋白：淀粉样前体蛋白家族的生理功能。

Nat Rev Neurosci. 2017 May;18(5):281-298. doi: 10.1038/nrn.2017.29. Epub 2017 Mar 31.

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Mol Cancer Res. 2015 May;13(5):809-18. doi: 10.1158/1541-7786.MCR-14-0241. Epub 2015 Feb 12.

(-)-Epigallocatechin-3-gallate induces cancer cell apoptosis via acetylation of amyloid precursor protein.（-）-表没食子儿茶素-3-没食子酸酯通过淀粉样前体蛋白的乙酰化诱导癌细胞凋亡。

Med Oncol. 2015 Jan;32(1):390. doi: 10.1007/s12032-014-0390-0. Epub 2014 Dec 2.

Silencing ADAM10 inhibits the in vitro and in vivo growth of hepatocellular carcinoma cancer cells.沉默ADAM10可抑制肝癌细胞的体外和体内生长。

Mol Med Rep. 2015 Jan;11(1):597-602. doi: 10.3892/mmr.2014.2652. Epub 2014 Oct 15.

HuD regulates coding and noncoding RNA to induce APP→Aβ processing.HuD调节编码和非编码RNA以诱导APP→Aβ加工。

Cell Rep. 2014 Jun 12;7(5):1401-1409. doi: 10.1016/j.celrep.2014.04.050. Epub 2014 May 22.

Isolated limb infusion with melphalan and actinomycin D for melanoma: a systematic review.甲氨蝶呤和放线菌素 D 单独肢体输注治疗黑色素瘤：系统评价。

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A novel role of HuR in -Epigallocatechin-3-gallate (EGCG) induces tumour cells apoptosis.

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