Hougardy L, Alexandrescu A, Piret S, Van Ouytsel F, Kerzmann B
Service des Urgences, Clinique Notre-Dame de Grâce, Gosselies, Belgique.
Rev Med Liege. 2019 Feb;74(2):71-73.
The use of extracorporeal membrane oxygenation (ECMO) in severe hypothermia associated with cardiac arrest has become a more frequent warming technique in specialized centers over the years with better survival outcomes compared to traditional rewarming methods. We show that a full recovery is possible, even after prolonged resuscitation. We report the case of a 36-year old male who survived approximately 4 hours of cardiopulmonary resuscitation following an unknown duration of asystole in the context of severe accidental hypothermia (24°C). Normal sinus rhythm was obtained using a single external electric shock during the rewarming of the patient by ECMO. After a hospital stay of 17 days, there were no neurological deficits and he achieved a full recovery. Although prolonged out-of-hospital cardiac arrest has low survival rates and asystole is not generally considered as an indication for extracorporeal cardiopulmonary resuscitation (ECCPR), associated hypothermia can be a predictor of a possible positive outcome when ECMO is used as it reduces the metabolism and protects the brain, thus leading to "miraculous" recoveries with no neurological sequelae. This case demonstrates yet again the importance of advanced rewarming techniques such as ECMO in the outcome of patients with severe accidental hypothermia, even after prolonged and refractory out-of hospital cardiac arrest and when "no-flow" time is uncertain. It also highlights the need for accidental hypothermia treatment algorithms, especially in hospitals capable of ECMO rewarming, to enable more rapid decision-making.
多年来,在与心脏骤停相关的严重低温治疗中,体外膜肺氧合(ECMO)在专业中心已成为一种更常用的复温技术,与传统复温方法相比,其生存结局更好。我们证明,即使经过长时间复苏,完全康复也是可能的。我们报告了一例36岁男性病例,该患者在严重意外低温(24°C)情况下,在心脏停搏持续时间不明后,接受了约4小时的心肺复苏并存活。在通过ECMO对患者进行复温期间,单次体外电击后恢复了正常窦性心律。住院17天后,患者无神经功能缺损,实现了完全康复。尽管院外心脏骤停时间延长的生存率较低,且心脏停搏一般不被视为体外心肺复苏(ECCPR)的指征,但当使用ECMO时,相关的低温可能是预后良好的一个预测指标,因为它可降低新陈代谢并保护大脑,从而实现“奇迹般”的康复且无神经后遗症。该病例再次证明了先进的复温技术如ECMO在严重意外低温患者预后中的重要性,即使是在院外心脏骤停时间延长且难以复苏以及“无血流”时间不确定的情况下。它还强调了制定意外低温治疗算法的必要性,特别是在有能力进行ECMO复温的医院,以便能够更快地做出决策。