Garner W L, Marx M V, Fabri P J
Department of Surgery, Ohio State University College of Medicine, Columbus.
Am J Surg. 1988 Jun;155(6):727-9. doi: 10.1016/s0002-9610(88)80030-8.
Critical review of cholescintigraphy in critically ill patients suggests the examination will not conclusively prove or disprove the diagnosis of acute cholecystitis. Of 17 scans performed in critically ill patients with clinical evidence of acute cholecystitis, 7 were true-negative, 1 was false-negative, 6 were false-positive, and 3 were nondiagnostic. Cholestasis and hepatocyte dysfunction, common in the critically ill, result in abnormal clearance of hepatobiliary radionuclide imaging agents, decreasing the usefulness of cholescintigraphy in this patient population. Diagnosing acute cholecystitis in a critically ill patient remains difficult.
对危重症患者进行的胆囊闪烁扫描的严格审查表明，该检查无法确凿地证实或排除急性胆囊炎的诊断。在17例有急性胆囊炎临床证据的危重症患者中进行的扫描中，7例为真阴性，1例为假阴性，6例为假阳性，3例为非诊断性。胆汁淤积和肝细胞功能障碍在危重症患者中很常见，会导致肝胆放射性核素显像剂清除异常，降低胆囊闪烁扫描在该患者群体中的实用性。在危重症患者中诊断急性胆囊炎仍然很困难。
