[Effect of highly purified thymus factor on the cellular and humoral indices of immunity in thymectomized mice].
作者信息
Belokrylov G A, Morozov V G, Khavinson V Kh, Sofronov B N
出版信息
Biull Eksp Biol Med. 1978;86(7):51-53.
PMID:307966
Abstract
Effect of homogeneous polypeptide thymus factor of mol weight about 5000 (thymarin-III) on cellular and humoral immune responses of thymectomized adult CBA mice was studied. Thymectomy proved to greatly decrease the number of T-cells in the spleen. Accordingly, the capability of these mice to produce both IgM and IgG antibody-forming cells in response to the thymus-dependent antigen (sheep red blood cells) was significantly depressed. Subcutaneous injections of thymarin-III (1 microgram per g of body weight) for 7 days completely restored the T-cell spleen population and normalized the animals' immune response.
摘要
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[Effect of highly purified thymus factor on the cellular and humoral indices of immunity in thymectomized mice].
Biull Eksp Biol Med. 1978;86(7):51-53.
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