Department of Psychology, University of Cyprus, Cyprus.
School of Psychology, Victoria University of Wellington, New Zealand.
Neurosci Biobehav Rev. 2019 May;100:98-107. doi: 10.1016/j.neubiorev.2019.02.016. Epub 2019 Feb 21.
The aim of this study was to conduct a systematic review of the literature and meta-analysis to estimate the association between psychophysiological activity and reactivity at baseline or after a psychological task with conduct problems (CP) among children and adolescents. We systematically reviewed published studies reporting autonomic nervous system activity in youth with CP and meta-analyzed the relationship between CP and autonomic baseline as well as task-related reactivity in 66 studies (N = 10,227). Across 34 included case-control studies that were based on CP cut-off scores, we found a significant pooled effect for task related Skin-Conductance, Respiratory Sinus Arrhythmia, and cardiac Pre-Ejection Period, but no significant group differences for Heart Rate nor for any baseline measures. Findings suggested reduced parasympathetic and sympathetic reactivity to emotional tasks, pointing to co-inhibition of the two systems. However, across 32 studies with correlational design we only found a significant negative correlation of baseline and task-related heart rate with CP. The present meta-analysis derived several conclusions that have the potential to inform biological vulnerability models and biologically driven interventions.
本研究旨在进行系统文献回顾和荟萃分析，以评估儿童和青少年在基线或完成心理任务后的心理生理活动和反应与行为问题（CP）之间的相关性。我们系统地回顾了报道青少年 CP 自主神经系统活动的已发表研究，并对 66 项研究（N=10227）中 CP 与自主基线以及与任务相关的反应性之间的关系进行了荟萃分析。在基于 CP 临界值评分的 34 项纳入的病例对照研究中，我们发现与任务相关的皮肤传导、呼吸窦性心律失常和心脏射前期存在显著的汇总效应，但心率和任何基线测量均无显著的组间差异。研究结果表明，情绪任务的副交感神经和交感神经反应性降低，表明两个系统的共同抑制。然而，在 32 项具有相关性设计的研究中，我们仅发现基线和与任务相关的心率与 CP 呈显著负相关。本荟萃分析得出了一些结论，这些结论有可能为生物易感性模型和基于生物学的干预措施提供信息。
