St. Josephs Hospital, Tampa, FL, USA.
The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Ann Diagn Pathol. 2019 Apr;39:74-77. doi: 10.1016/j.anndiagpath.2019.02.014. Epub 2019 Feb 19.
Malignant Mesothelioma is an uncommon tumor that usually presents with diffuse pleural involvement and carries a dismal prognosis. Rarely, however, it can present as a localized, circumscribed mass or focal pleural lesion without evidence of diffuse spread. We found four such cases in our database. Three patients had localized epithelioid malignant mesothelioma and one had localized sarcomatoid mesothelioma. These localized tumors are a potential diagnostic pitfall for the pathologists as well as radiologists, especially those practicing in a community setting. Herein we discuss the clinicopathologic features of our cases along with a review of literature.
恶性间皮瘤是一种罕见的肿瘤,通常表现为弥漫性胸膜受累,并伴有预后不良。然而,它也很少表现为局限性、局限性肿块或局灶性胸膜病变,而没有弥漫性播散的证据。我们在数据库中发现了四个这样的病例。三例为局限性上皮样恶性间皮瘤,一例为局限性肉瘤样间皮瘤。这些局限性肿瘤是病理学家和放射科医生的潜在诊断陷阱,尤其是在社区环境中工作的医生。本文讨论了我们病例的临床病理特征,并复习了文献。