Bona R D, Pasquale D N, Kalish R I, Witter B A
Am J Hematol. 1986 Feb;21(2):201-7. doi: 10.1002/ajh.2830210209.
Management of hemophiliac patients with inhibitors can be a difficult problem. We report here a patient with severe hemophilia A, a high titer inhibitor, and an abdominal abscess requiring surgery. Despite significant cross reactivity of the inhibitor with porcine FVIII, he was successfully managed with plasmapheresis and porcine FVIII infusions. Other approaches to the management of such patients are briefly reviewed.
对伴有抑制物的血友病患者进行管理可能是个难题。我们在此报告一名患有严重甲型血友病、高滴度抑制物且患有需要手术治疗的腹部脓肿的患者。尽管该抑制物与猪源FVIII有显著交叉反应，但通过血浆置换和猪源FVIII输注，他得到了成功治疗。本文还简要回顾了对此类患者进行管理的其他方法。
