Clinic of Orthodontics and Pediatric Dentistry, Center of Dental Medicine, University of Zurich, Plattenstrasse 11, CH-8032, Zurich, Switzerland.
Prog Orthod. 2019 Feb 25;20(1):9. doi: 10.1186/s40510-019-0261-5.
The aim of the current systematic review was to compare the clinical effects of bone-borne or hybrid tooth-bone-borne rapid maxillary expansion (RME) with conventional tooth-borne RME in the treatment of maxillary deficiency.
Nine databases were searched up to September 2018 for randomized clinical trials comparing bone-borne or hybrid tooth-bone-borne RME to conventional tooth-borne RME in patients of any age or sex. After duplicate study selection, data extraction, and risk of bias assessment with the Cochrane tool, random effects meta-analyses of mean differences (MD) and their 95% confidence intervals (CIs) were performed, followed by assessment of the quality of evidence with GRADE.
A total of 12 papers on 6 unique trials with 264 patients (42.4% male; average age 12.3 years) were finally included. Limited evidence indicated that bone-borne RME was associated with greater suture opening at the first molar post-retention (1 trial; MD 2.0 mm; 95% CI 1.4 to 2.6 mm; moderate evidence quality) compared to tooth-borne RME, while no significant differences could be found regarding tooth inclination, nasal cavity width, and root resorption (very low to low evidence quality). Hybrid tooth-bone-borne RME was associated with less buccal tipping of the first premolar (2 trials; MD - 4.0°; 95% CI - 0.9 to - 7.1°; moderate evidence quality) and lower nasal airway resistance post-retention (1 trial; MD - 0.2 Pa s/cm; 95% CI - 0.4 to 0 Pa s/cm; moderate evidence quality) compared to tooth-borne RME, while no significant difference could be found regarding skeletal maxillary width, molar inclination, and analgesic use (low to moderate evidence quality). The main limitations affecting the validity of the present findings were (a) imprecision due to the inclusion of few trials with limited sample sizes that precluded robust detection of existing differences and (b) methodological issues of the included trials that could lead to bias.
Limited evidence from randomized trials indicates that bone-borne or hybrid tooth-bone-borne RME might present advantages in terms of increased sutural opening, reduced tooth tipping, and lower nasal airway resistance compared to conventional tooth-borne RME. However, the limited number of existing studies and issues in their conduct or reporting preclude the drawing of definite conclusions.
PROSPERO ( CRD42017079107 ).
本系统评价的目的是比较骨支或混合牙-骨支快速上颌扩张(RME)与传统牙支 RME 在治疗上颌骨不足方面的临床效果。
截至 2018 年 9 月,我们在 9 个数据库中检索了比较任何年龄或性别的患者使用骨支或混合牙-骨支 RME 与传统牙支 RME 的随机临床试验。经过重复研究选择、数据提取和使用 Cochrane 工具进行偏倚风险评估后,我们进行了均值差(MD)及其 95%置信区间(CI)的随机效应荟萃分析,随后使用 GRADE 评估证据质量。
最终纳入了 12 篇论文,涉及 6 项独特的试验,共有 264 名患者(42.4%为男性;平均年龄 12.3 岁)。有限的证据表明,与牙支 RME 相比,骨支 RME 与第一磨牙在保持后的更大的骨缝打开有关(1 项试验;MD 2.0mm;95%CI 1.4 至 2.6mm;证据质量为中等),而牙齿倾斜度、鼻腔宽度和牙根吸收没有显著差异(证据质量为极低至低)。混合牙-骨支 RME 与第一前磨牙颊向倾斜度较小有关(2 项试验;MD -4.0°;95%CI -0.9 至-7.1°;证据质量为中等),保持后鼻腔气道阻力较低(1 项试验;MD -0.2Pa·s/cm;95%CI -0.4 至 0Pa·s/cm;证据质量为中等)与牙支 RME 相比,而骨骼上颌宽度、磨牙倾斜度和镇痛剂使用方面没有显著差异(证据质量为低至中)。影响本研究结果有效性的主要局限性是(a)由于纳入的试验数量有限且样本量有限,导致无法稳健地检测到现有差异,因此存在不精确性;(b)纳入试验的方法学问题可能导致偏倚。
随机试验的有限证据表明,与传统牙支 RME 相比,骨支或混合牙-骨支 RME 可能在增加骨缝打开、减少牙齿倾斜和降低鼻腔气道阻力方面具有优势。然而,现有研究数量有限,且在实施或报告方面存在问题,因此无法得出明确的结论。
PROSPERO(CRD42017079107)。