Malik Azeem Tariq, Quatman Carmen E, Phieffer Laura S, Ly Thuan V, Khan Safdar N
Department of Orthopaedics, The Ohio State University Wexner Medical Center, OH, USA.
Hip Int. 2020 Jan;30(1):22-32. doi: 10.1177/1120700019831950. Epub 2019 Feb 25.
We compiled evidence from a large national surgical database to identify the incidence, risk factors and postoperative impact of infection (CDI) in patients undergoing hip fracture repair.
We identified 17,474 patients who underwent hip fracture repairs in 2015 using the ACS-NSQIP database. Interventions studied were open reduction/Internal fixation, total hip arthroplasty or hemiarthroplasty being performed for traumatic hip fractures. Outcomes studied were incidence, preoperative and postoperative risk factors for occurrence of CDI were studied using descriptive and statistical analysis.
A total of 92 patients (0.53%) developed CDI within 30 days of the operation. Following adjustment using multi-variate logistic regression, preoperative and hospital-associated factors associated with development of CDI were smoking (OR 1.75 [95% CI 1.03-2.99]), hypertension (OR 1.70 [95% CI 1.01-2.85]), hyponatraemia (OR 1.65 [95% CI 1.04-2.63]), prior systemic inflammatory response syndrome (SIRS) (OR 2.18 [95% CI 1.32-3.59]) and a length of stay >7 days (OR 1.98 [95% CI 1.11-3.53]. Postoperative factors associated with occurrence of CDI were occurrence of a deep surgical site infection (SSI) (OR 5.89 [95% CI 1.31-26.6]), a stay in the hospital >30 days (OR 6.56 [95% CI 2.56-16.9]) and unplanned reoperations (OR 2.78 [95% CI 1.29-5.99]).
As we move toward an era of bundled-payment models, identification of risk factors associated with the occurrence of postoperative complications, such as CDI, will help curb excess healthcare utilisation and costs associated with the management of this complication.
我们从一个大型国家外科手术数据库中收集证据,以确定髋部骨折修复患者中艰难梭菌感染(CDI)的发生率、危险因素及术后影响。
我们使用美国外科医师学会国家外科质量改进计划(ACS-NSQIP)数据库,确定了2015年接受髋部骨折修复的17474例患者。所研究的干预措施为针对创伤性髋部骨折进行切开复位/内固定、全髋关节置换术或半髋关节置换术。所研究的结果为CDI的发生率,术前及术后发生CDI的危险因素通过描述性和统计分析进行研究。
共有92例患者(0.53%)在术后30天内发生CDI。经多变量逻辑回归调整后,与CDI发生相关的术前及医院相关因素包括吸烟(比值比[OR]1.75[95%置信区间(CI)1.03 - 2.99])、高血压(OR 1.70[95%CI 1.01 - 2.85])、低钠血症(OR 1.65[95%CI 1.04 - 2.63])、既往全身炎症反应综合征(SIRS)(OR 2.18[95%CI 1.32 - 3.59])以及住院时间>7天(OR 1.98[95%CI 1.11 - 3.53])。与CDI发生相关的术后因素包括深部手术部位感染(SSI)(OR 5.89[95%CI 1.31 - 26.6])、住院时间>30天(OR 6.56[95%CI 2.56 - 16.9])以及非计划再次手术(OR 2.78[95%CI 1.29 - 5.99])。
随着我们迈向捆绑支付模式的时代,识别与术后并发症(如CDI)发生相关的危险因素,将有助于控制过度的医疗资源利用以及与该并发症管理相关的成本。