Bhakhri Raman, Ridder William H, Adrean Sean
Southern California College of Optometry, Marshall B. Ketchum University, Fullerton, California.
Retina Consultants of Orange County, Los Alamitos, California *
Optom Vis Sci. 2019 Mar;96(3):227-232. doi: 10.1097/OPX.0000000000001346.
Although rare, vitamin A retinopathy should be considered by the clinicians in their differentials for conditions that can lead to nyctalopia, especially in those patients who have undergone bariatric surgery. Patients must be educated on this potential delayed adverse effect of the surgery and possible lifelong vitamin A supplementation.
The purpose of this study was to report a rare case of delayed vitamin A retinopathy that occurred because of vitamin A malabsorption secondary to bariatric surgery.
A 55-year-old woman presented with nyctalopia and dark adaptation problems. The patient had a history of gastric bypass surgery 22 years earlier. Fundus examination revealed a large number of small white dots in the midperiphery of both eyes. Electrophysiology testing revealed flat-lined scotopic responses. Vitamin A levels were found to be severely reduced. Subsequent vitamin A supplementation resulted in the reversal of all signs and symptoms.
This case report demonstrates the importance of considering vitamin A deficiency in patients who present with symptoms of nyctalopia with a history of bariatric surgery. Clinicians should be aware of a possible delayed onset and refer for appropriate testing and treatment, as vitamin A retinopathy has been shown to be reversible. Because other conditions can present with nyctalopia and retinal white spots, clinicians also need to consider the appropriate differential diagnoses. Lifelong monitoring is indicated because reoccurrences have been reported.
尽管罕见,但临床医生在鉴别导致夜盲症的病症时应考虑维生素A视网膜病变,尤其是那些接受过减肥手术的患者。必须让患者了解手术这种潜在的延迟不良反应以及可能需要终身补充维生素A的情况。
本研究的目的是报告一例因减肥手术继发维生素A吸收不良而发生的罕见迟发性维生素A视网膜病变病例。
一名55岁女性出现夜盲症和暗适应问题。该患者22年前有胃旁路手术史。眼底检查发现双眼中外周有大量小白点。电生理测试显示暗视反应呈平线。发现维生素A水平严重降低。随后补充维生素A后,所有体征和症状均得到逆转。
本病例报告证明了在有减肥手术史且出现夜盲症症状的患者中考虑维生素A缺乏的重要性。临床医生应意识到可能存在延迟发作,并进行适当的检查和治疗,因为维生素A视网膜病变已被证明是可逆的。由于其他病症也可能出现夜盲症和视网膜白点,临床医生还需要考虑适当的鉴别诊断。鉴于有复发的报道,需要进行终身监测。