低肌肉量老年人体脂百分比的预测价值：一项为期 2.2 年的纵向研究。

Predictive value of percentage body fat in aging people with low muscle mass: A 2.2-year longitudinal study.

机构信息

Department of Geriatric Cardiology, Chinese PLA General Hospital, No.28 Fuxing Road, Haidian District, Beijing, China.

Department of Rehabilitation, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China; Department of Rehabilitation, Chinese PLA General Hospital, Beijing, China.

出版信息

Arch Gerontol Geriatr. 2019 May-Jun;82:167-171. doi: 10.1016/j.archger.2019.02.005. Epub 2019 Feb 18.

DOI:10.1016/j.archger.2019.02.005

PMID:30802841

Abstract

BACKGROUND

The aim of this study was to evaluate the usefulness of percentage body fat (PBF) in screening for the risk of low muscle mass (LMM) in elderly people.

METHODS

A prospective study was carried out in Chinese PLA General Hospital with 413 participants who underwent baseline and an average 2.2-year follow-up health check-up examinations.

RESULTS

The average age of the participants at baseline was 63.6 years. The incidence of newly developed LMM was 10.3% in men and 18.2% in women during follow-up. Linear regression demonstrated that baseline PBF were negatively correlated with follow-up total muscle mass index (TMMI) in both men and women (β=-0.124 for men and -0.233 for women, all P < 0.001). The cut-off points of baseline PBF in elderly people for future LMM were 25.45% in men and 30.95% in women and were identified by Receiver Operator Curves (ROC).

CONCLUSIONS

Elderly people with a high PBF had a higher risk of new LMM, which suggested that baseline PBF had a close relationship with future LMM and the screening of high PBF should be paid enough attention in health care management in the senior people.

摘要

背景

本研究旨在评估体脂肪百分比（PBF）在筛查老年人低肌肉量（LMM）风险中的有用性。

方法

在中国人民解放军总医院进行了一项前瞻性研究，共有 413 名参与者接受了基线和平均 2.2 年的随访健康检查。

结果

参与者的平均基线年龄为 63.6 岁。在随访期间，男性新发生 LMM 的发生率为 10.3%，女性为 18.2%。线性回归表明，基线 PBF 与男性和女性的随访总肌肉量指数（TMMI）呈负相关（男性β=-0.124，女性β=-0.233，均 P<0.001）。通过受试者工作特征曲线（ROC）确定，基线 PBF 是老年人未来发生 LMM 的截定点，男性为 25.45%，女性为 30.95%。