Boddeda Kondala Rao, Rani Ch Radha, V Vanga Narsimha Rao, Chandrabhatla Srinivas Kumar
Department of Pedodontics and Preventive Dentistry, GITAM dental College and Hospital, Visakhapatnam, Andhra Pradesh, India.
J Indian Soc Pedod Prev Dent. 2019 Jan-Mar;37(1):60-66. doi: 10.4103/JISPPD.JISPPD_213_17.
Indirect pulp therapy (IPT) is conventional treatment of deep dentinal carious lesions without risk of pulp exposure. Development of new biomaterials with biocompatibility and seal has changed the attitudes toward IPT.
AIM/OBJECTIVES: This study was conducted to evaluate and compare the clinical and radiographic success of biodentine, 2% chlorhexidine gluconate with resin-modified glass ionomer cement (RMGIC), and calcium hydroxide as indirect pulp-capping materials in primary molars over an observation period of 12 months.
A total of 54 primary molars within the age group of 3-9 years, which were indicated for IPT were randomized into three groups of 18 samples each; Group I: biodentine, Group II: 2% chlorhexidine gluconate followed by RMGIC, Group III: calcium hydroxide (Dycal). These cases were followed up for evaluation clinically and radiographically at 3, 6, and 12 months. The recorded data were subjected to statistical analysis using Chi-square test.
After 12 months, the clinical and radiographic success of biodentine group was 100% (18/18), with 2% chlorhexidine gluconate disinfecting solution followed by RMGIC was 94.4% (17/18) and calcium hydroxide (Dycal) was 94.4% (17/18), failures included one at 3 months with RMGIC and another at 12 months with calcium hydroxide group; but there was no statistically significant difference observed between them with P = 0.361 at 3 months and P = 0.371 at 12 months interval.
Biodentine can be effectively used as indirect pulp-capping medicament in primary teeth which has similar clinical and radiographic success as 2% chlorhexidine gluconate in conjunction with RMGIC and calcium hydroxide.
间接盖髓术（IPT）是治疗深龋牙本质病变且无牙髓暴露风险的传统方法。具有生物相容性和封闭性的新型生物材料的出现改变了人们对IPT的看法。
本研究旨在评估和比较生物陶瓷、2%葡萄糖酸氯己定与树脂改性玻璃离子水门汀（RMGIC）以及氢氧化钙作为间接盖髓材料在乳牙中应用12个月的临床和影像学成功率。
将54颗年龄在3至9岁、适合进行IPT的乳牙随机分为三组，每组18个样本；第一组：生物陶瓷；第二组：2%葡萄糖酸氯己定后用RMGIC；第三组：氢氧化钙（Dycal）。在3、6和12个月时对这些病例进行临床和影像学评估随访。对记录的数据采用卡方检验进行统计分析。
12个月后，生物陶瓷组的临床和影像学成功率为100%（18/18），2%葡萄糖酸氯己定消毒溶液后用RMGIC组为94.4%（17/18），氢氧化钙（Dycal）组为94.4%（17/18），失败病例包括1例3个月时RMGIC组的和1例12个月时氢氧化钙组的；但在3个月时P = 0.361，12个月时P = 0.371，两组间差异无统计学意义。
生物陶瓷可有效用作乳牙间接盖髓药物，其临床和影像学成功率与2%葡萄糖酸氯己定联合RMGIC以及氢氧化钙相似。
