Lolayekar Nikita V, Kadkhodayan Sharmin S
Department of Pedodontics and Preventive Dentistry, A B Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India.
Intern, A B Shetty Memorial Institute of Dental Sciences, Nitte University, Mangalore, Karnataka, India.
J Indian Soc Pedod Prev Dent. 2019 Jan-Mar;37(1):87-91. doi: 10.4103/JISPPD.JISPPD_91_17.
The current concepts of dental caries focus on cariogenic bacteria such as Streptococcus mutans fermenting carbohydrates to form organic acids, which cause a drop in pH, resulting in demineralization of the tooth surface. Studies show that Tulsi has broad-spectrum antimicrobial activity. Hence, this study aimed at estimating the change in salivary pH and viability of S. mutans on chewing of Tulsi leaves, in children.
This study aimed to estimate the change in salivary pH and viability of S. mutans on chewing of Tulsi leaves.
The study was carried out on thirty children aged 9-12 years. Oral prophylaxis was performed prior to sample collection. Three samples were collected per child, one before and two after chewing of Tulsi leaves. The change in salivary pH and viability of S. mutans was assessed.
The obtained data were analyzed using Friedman test and Wilcoxon's test. The level of significance was set at P < 0.05.
The results obtained showed no significant difference in the pH values obtained from the samples, but there was a significant difference in the S. mutans' colony counts.
Based on the results obtained from this study, it may be concluded that Tulsi (Ocimum sanctum) has the potential to be developed into an antimicrobial agent against cariogenic bacteria, specifically S. mutans.
目前关于龋齿的概念聚焦于致龋菌,如变形链球菌将碳水化合物发酵形成有机酸,导致pH值下降,从而使牙齿表面脱矿。研究表明,罗勒具有广谱抗菌活性。因此,本研究旨在评估儿童咀嚼罗勒叶后唾液pH值的变化以及变形链球菌的生存能力。
本研究旨在评估儿童咀嚼罗勒叶后唾液pH值的变化以及变形链球菌的生存能力。
本研究对30名9至12岁的儿童进行。在采集样本前进行口腔预防措施。每个儿童采集三个样本,一个在咀嚼罗勒叶前,两个在咀嚼罗勒叶后。评估唾液pH值的变化以及变形链球菌的生存能力。
使用弗里德曼检验和威尔科克森检验对所得数据进行分析。显著性水平设定为P < 0.05。
所得结果显示,样本的pH值无显著差异,但变形链球菌的菌落计数有显著差异。
基于本研究所得结果,可以得出结论,罗勒(神圣罗勒)有潜力被开发成一种针对致龋菌,特别是变形链球菌的抗菌剂。