Khan Muhammad Rizwan, Begum Saleema
Aga Khan University, KARACHI, PAKISTAN.
J Pak Med Assoc. 2019 Feb;69(2):256-260.
Xanthogranulomatous cholecystitis is a rare variant of chronic cholecystitis, which can involve adjacent organs including liver, colon and duodenum mimicking gallbladder cancer. Preoperative and intraoperative differentiation of xanthogranulomatous cholecystitis from gallbladder cancer is often difficult and the final diagnosis is made on histopathology of the resected specimen. We hereby report four cases of xanthogranulomatous chol ec ystitis w hich were misdiagnosed as cases of advanced gallbladder cancer based on presentation and radiological findings and underwent radical resections but the final histopathology was a diagnostic surprise. Xanthogranulomatous cholecystitis is still a diagnostic challenge as no single modality has been helpful to diagnose this entity till date. Radical resection seems justified in patients who present with the features mimicking gallbladder cancer.
黄色肉芽肿性胆囊炎是一种罕见的慢性胆囊炎变体，可累及包括肝脏、结肠和十二指肠在内的邻近器官，酷似胆囊癌。术前及术中将黄色肉芽肿性胆囊炎与胆囊癌区分开来往往很困难，最终诊断需依据切除标本的组织病理学检查。我们在此报告4例黄色肉芽肿性胆囊炎病例，这些病例根据临床表现和影像学检查结果被误诊为晚期胆囊癌，并接受了根治性切除术，但最终的组织病理学检查结果令人惊讶。黄色肉芽肿性胆囊炎至今仍是一个诊断难题，因为目前尚无单一方法有助于诊断该病。对于表现出类似胆囊癌特征的患者，进行根治性切除似乎是合理的。
