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乳腺磁共振成像:在导管原位癌评估中的作用

Magnetic resonance imaging of the breast: role in the evaluation of ductal carcinoma in situ.

作者信息

Tajima Carla Chizuru, de Sousa Luiza Lourenço Campos, Venys Gustavo Lagreca, Guatelli Camila Souza, Bitencourt Almir Galvão Vieira, Marques Elvira Ferreira

机构信息

Departamento de Imagem - A.C.Camargo Cancer Center, São Paulo, SP, Brazil.

出版信息

Radiol Bras. 2019 Jan-Feb;52(1):43-47. doi: 10.1590/0100-3984.2018.0058.

Abstract

Ductal carcinoma in situ (DCIS) is a precursor mammary lesion whose malignant cells do not extend beyond the basement membrane and presents a risk of progression to malignant disease. Its early detection increased with screening mammography. The objective of this study was to review the literature on the main presentations of DCIS on magnetic resonance imaging (MRI), through searches of the Medline/PubMed, Latin-American and Caribbean Center on Health Sciences Information (Lilacs), and Scientific Electronic Library Online (SciELO) databases. DCIS can occur in its pure form or in conjunction with invasive disease, in the same lesion, in different foci, or in the contralateral breast. MRI has a high sensitivity for the detection of pure DCIS, being able to identify the non-calcified component, and its accuracy increases with the nuclear grade of the lesion. The most common pattern of presentation is non-nodular enhancement; heterogeneous internal structures; a kinetic curve showing washout or plateau enhancement; segmental distribution; and restricted diffusion. MRI plays an important role in the detection of DCIS, especially in the evaluation of its extent, contributing to more reliable surgical excision and reducing local recurrence.

摘要

导管原位癌(DCIS)是一种乳腺前驱性病变,其恶性细胞不会延伸至基底膜以外,存在进展为恶性疾病的风险。随着乳腺钼靶筛查的开展,其早期检出率有所提高。本研究的目的是通过检索Medline/PubMed、拉丁美洲和加勒比地区卫生科学信息中心(Lilacs)以及科学电子图书馆在线(SciELO)数据库,回顾关于DCIS在磁共振成像(MRI)上主要表现的文献。DCIS可以以纯形式出现,也可与浸润性疾病同时出现,可在同一病变、不同病灶或对侧乳房中出现。MRI对纯DCIS的检测具有高敏感性,能够识别非钙化成分,其准确性随着病变的核分级增加而提高。最常见的表现模式为非结节状强化;内部结构不均匀;动态曲线显示廓清或平台期强化;节段性分布;以及扩散受限。MRI在DCIS的检测中发挥着重要作用,尤其是在评估其范围方面,有助于更可靠的手术切除并减少局部复发。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b65/6383537/b8a264883d21/rb-52-01-0043-g01.jpg

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