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直肠癌手术后功能失调造口的逆转:我们是否做得更好?一项基于人群的单中心经验。

Reversal of defunctioning stoma following rectal cancer surgery: are we getting better? A population-based single centre experience.

作者信息

Gadan Soran, Lindgren Rickard, Floodeen Hannah, Matthiessen Peter

机构信息

Department of Surgery, Örebro University Hospital, Örebro, Sweden.

Department of Surgery, Faculty of Medicine and Health, School of Health and Medical Sciences, Örebro University, Örebro, Sweden.

出版信息

ANZ J Surg. 2019 Apr;89(4):403-407. doi: 10.1111/ans.14990. Epub 2019 Feb 25.

Abstract

BACKGROUND

The aim was to assess factors influencing the timing of defunctioning stoma (DS) reversal following low anterior resection of rectum for cancer (LAR).

METHODS

All patients operated with LAR and a primary DS during a 9-year period were included. Reversal later than 120 days after LAR was considered as delayed. A DS not reversed within 2 years was considered as permanent.

RESULTS

In the present study, median age at LAR was 67 years, 45% were females, median body mass index was 25, 87% had American Society of Anesthesiologists class I or II, 64% had pre-operative radiotherapy, and 3% had cancer stage IV. A total of 79% (92/116) underwent stoma reversal, whereof 25% (23/92) were reversed within 120 days. The most common health-related reasons for delayed stoma reversal were adjuvant chemotherapy in 38%, symptomatic anastomotic leakage in 16% and other post-operative adverse events in 13%. In 35% delayed stoma reversal was because of low priority within the healthcare system. A total of 18% (20/110) never had their DS reversed (n = 11) or had their DS converted to a permanent end colostomy (n = 9). Major risk factors for permanent stoma were stage IV cancer in 55%, and symptomatic anastomotic leakage in 30%.

CONCLUSION

One fourth of the patients had their defunctioning stoma reversed within 120 days. The most common identifiable medical reasons for delayed stoma reversal were adjuvant chemotherapy and symptomatic anastomotic leakage, while in one out of three patients it was because of low priority by the healthcare provider.

摘要

背景

目的是评估影响直肠癌低位前切除术(LAR)后造口减压术(DS)回纳时机的因素。

方法

纳入9年间所有接受LAR并进行一期DS手术的患者。LAR术后超过120天回纳造口被视为延迟回纳。2年内未回纳的DS被视为永久性造口。

结果

在本研究中,LAR时的中位年龄为67岁,45%为女性,中位体重指数为25,87%的患者美国麻醉医师协会分级为I或II级,64%接受过术前放疗,3%为癌症IV期。共有79%(92/116)的患者进行了造口回纳,其中25%(23/92)在120天内回纳。造口延迟回纳最常见的与健康相关的原因是辅助化疗占38%,有症状的吻合口漏占16%,其他术后不良事件占13%。35%的造口延迟回纳是因为在医疗系统中优先级较低。共有18%(20/110)的患者从未回纳其DS(n = 11)或其DS被改为永久性结肠造口(n = 9)。永久性造口的主要危险因素是IV期癌症占55%,有症状的吻合口漏占30%。

结论

四分之一的患者在120天内回纳了造口减压术造口。造口延迟回纳最常见的可识别医学原因是辅助化疗和有症状的吻合口漏,而三分之一的患者是因为医疗服务提供者的优先级较低。

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